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D8668

2′-Deoxyadenosine monohydrate

Name: 2′-Deoxyadenosine monohydrate
Brand: SIGMA

powder, BioReagent, suitable for cell culture

Synonyme(s) :

9-(2-Deoxy-β-D-ribofuranosyl)adenine, Adenine deoxyriboside

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A propos de cet article

Formule empirique (notation de Hill) :

C₁₀H₁₃N₅O₃ · H₂O

Numéro CAS:

16373-93-6

Poids moléculaire :

269.26

UNSPSC Code:

12352207

NACRES:

NA.75

PubChem Substance ID:

24894112

EC Number:

213-488-7

Beilstein/REAXYS Number:

91015

MDL number:

MFCD00005754

Assay:

≥99% (HPLC)

Biological source:

synthetic (organic)

Form:

powder

Solubility:

H₂O: soluble 25 mg/mL, clear to slightly hazy, colorless to faintly yellow

Storage temp.:

2-8°C

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Propriétés

biological source

synthetic (organic)

Quality Segment

200

product line

BioReagent

assay

≥99% (HPLC)

form

powder

technique(s)

cell culture | mammalian: suitable

solubility

H₂O: soluble 25 mg/mL, clear to slightly hazy, colorless to faintly yellow

storage temp.

2-8°C

SMILES string

[H]O[H].Nc1ncnc2n(cnc12)[C@H]3C[C@H](O)[C@@H](CO)O3

InChI

1S/C10H13N5O3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(17)6(2-16)18-7/h3-7,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,7+/m0/s1

InChI key

OLXZPDWKRNYJJZ-RRKCRQDMSA-N

Description

Application

2′-Deoxyadenosine monohydrate has been used as a nucleotide precursor:

To study the importance of homologous recombination at the interface between replication and mitosis
To analyze deoxynucleoside-assisted transductions
To study the effect of increased deoxycytidine on gemcitabine resistance in pancreatic cancer cells

2′-Deoxyadenosine monohydrate has been used for the preparation of deoxyribonucleoside stock solution for the anaerobic culture of Bacillus mojavensis strains including JF-2 and two Bacillus subtilis strains.

Biochem/physiol Actions

Excess 2′-deoxyadenosine gets converted to adenosine triphosphate (dATP), which inhibits ribonucleotide reductase.

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Classe de stockage

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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