CS0410
Glutathione-S-Transferase (GST) Assay Kit
sufficient for 500 multiwell tests
Synonyme(s) :
GST Enzyme Activity Kit
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UNSPSC Code:
12161503
EC Number:
202-551-4
NACRES:
NA.84
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sufficient for 500 multiwell tests
Quality Segment
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... GSTA4(2941), GSTM1(2944)
General description
The Glutathione S-Transferase (GST) Assay Kit is designed to measure total GSTactivity. It can be used to measure GST activity in cell and bacterial lysates, tissue homogenates, and in plasma
and erythrocyte lysates
and erythrocyte lysates
Application
The Glutathione S-Transferase Assay kit utilizes 1-Chloro-2,4-dinitrobenzene (CDNB), which is suitable for the broadest range of GST isozymes. Upon conjugation of the thiol group of glutathione to the CDNB substrate, there is an increase in the absorbance at 340 nm.
Biochem/physiol Actions
Glutathione S-transferases (GSTs) are a group of enzymes important in the detoxification of many xenobiotics in mammals. The enzymes protect cells against toxicants by conjugating the thiol group of the glutathione to electrophilic xenobiotics, and thereby defend cells against the mutagenic, carcinogenic, and toxic effects of the compounds. GST activity is present in plants, insects, yeast, bacteria, and most mammalian tissues especially in the liver, which plays a key role in detoxification.
Composants de kit seuls
Réf. du produit
Description
- Dulbecco's Phosphate Buffered Saline 100 mL
L -Glutathione Reduced 1 g- GST (Control) .1 mL
- Sample Buffer 5 mL
- Substrate (CDNB) 1.2 mL
Mot-clé
Danger
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Codes de danger
Mentions de précaution
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 2 - Eye Irrit. 2 - Flam. Liq. 2 - Skin Sens. 1
Classe de stockage
3 - Flammable liquids
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