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C7263

Sigma-Aldrich

Calcium phosphate dibasic

98.0-105.0%

Synonyme(s) :

Calcium hydrogen phosphate

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About This Item

Formule linéaire :
CaHPO4
Numéro CAS:
7757-93-9
Poids moléculaire :
136.06
Numéro CE :
231-826-1
Numéro MDL:
MFCD00010909
Code UNSPSC :
12161700
ID de substance PubChem :
24892950
Nomenclature NACRES :
NA.25

Pureté

98.0-105.0%

Forme

powder

Chaîne SMILES 

[Ca++].OP([O-])([O-])=O

InChI

1S/Ca.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+2;/p-2

Clé InChI

FUFJGUQYACFECW-UHFFFAOYSA-L

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Application

Calcium phosphate dibasic has been used:
  • to prepare high temperature stoichiometric sintered hydroxyapatite (sin-HA)
  • as a component of calcium phosphate cement (CPC) to prepare bioartificial pancreas (BAP)
  • to produce calcium pyrophosphate (Ca2P2O7) for the preparation of α-tricalcium phosphates (α-TCP)

Actions biochimiques/physiologiques

Calcium phosphate dibasic is an anhydrate used to dilute tablets and capsules. It is widely used as an excipient for its compressibility, amenability, and brittle fracture propensity.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

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Sigma-Aldrich

693898

Tricalcium phosphate

Tribasic calcium phosphate United States Pharmacopeia (USP) Reference Standard

USP

1087031

Tribasic calcium phosphate

Anna Diez-Escudero et al.
Tissue engineering. Part C, Methods, 23(2), 118-124 (2017-01-14)
This article presents the application of dual focused ion beam/scanning electron microscopy (FIB-SEM) imaging for preclinical testing of calcium phosphates with osteoclast precursor cells and how this high-resolution imaging technique is able to reveal microstructural changes at a level of
Aditya M Kaushal et al.
Journal of pharmaceutical sciences, 100(4), 1456-1466 (2011-04-01)
Dibasic calcium phosphate occurs as an anhydrate (DCPA; CaHPO₄) and as a dihydrate (DCPD; CaHPO₄•2H₂O). Our objective was to investigate the unusual behavior of these phases. Dibasic calcium phosphate dihydrate was dehydrated in a (i) differential scanning calorimeter (DSC) in
Kai-Chiang Yang et al.
Transplantation, 90(6), 604-611 (2010-01-06)
Fibrous tissue outgrowth and hypoxia are the major restrictions for the application of bioartificial pancreas (BAP). Accordingly, the intramedullary cavity is proposed as an implant site, and a BAP constructed of calcium phosphate cement chamber was implanted. Mouse insulinoma cells
C L Camiré et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 79(1), 159-165 (2006-04-15)
Alpha phase tricalcium phosphates (alpha-TCP) were produced using a solid-state reaction method and milled for various periods of time. The resulting four materials were alpha-TCPs, ranging in crystalline content. Powders were exposed to X-ray diffraction for material identification as well
Tae-Woo Kim et al.
Tissue engineering and regenerative medicine, 17(5), 607-624 (2020-08-18)
The delivery of growth factors using a carrier system presents a promising and innovative tool in tissue engineering and dentistry today. Two of the foremost bioactive factors, bone morphogenetic protein-2 and vascular endothelial growth factor (VEGF), are widely applied using
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