Accéder au contenu
Merck
Toutes les photos(1)

Documents

C5608

Sigma-Aldrich

Collagen from rabbit skin

Bornstein and Traub Type I, powder

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme


About This Item

Numéro CAS:
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352202
Nomenclature NACRES :
NA.61

Source biologique

rabbit skin

Niveau de qualité

Description

acid soluble

Forme

powder

Technique(s)

cell culture | stem cell: suitable

Solubilité

aqueous acid: ≤10 mg/mL
aqueous sodium acetate buffer: soluble (0.01-0.5M)

Numéro d'accès UniProt

Température de stockage

2-8°C

Informations sur le gène

Description générale

Collagen is classified into a number of structurally and genetically distinct types. We use the nomenclature proposed by Bornstein and Traub. Do not confuse Sigma type designations with recognized collagen classification types.

Application

Collagen-type 1 may be used in research of Idiopathic pulmonary fibrosis (IPF). Robust expression of collagen-type 1 is one distinctive feature of IPF. Additionally, collagen-type 1 has been used in studies on the effect of endoplasmic reticulum (ER) stress from IPF on myofibroblastic differentiation of lung fibroblasts. Collage-type 1 soluble in acidic solution produces three dimensional scaffolding useful in bioengineering and cell culture applications where biomaterials are needed to replace native collagen extracellular matrices.

Collagen Type I has been used as a scaffold for the growth in vitro of stem cells in a wide variety of biomaterial engineering studies.

Notes préparatoires

Prepared with modification of Gallop, P.M.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Les clients ont également consulté

Prasad L Polavarapu et al.
Chirality, 23(9), 801-807 (2011-12-03)
Fourier transform infrared vibrational circular dichroism (FTIR-VCD) measurements have gone through major advances in the last decade. A major thrust in these advances was to find ways that can minimize the VCD spectral artifacts and obtain the VCD signals at
Simon Holland et al.
Current opinion in ophthalmology, 24(4), 302-309 (2013-05-18)
Topography-guided laser refractive surgery regularizes the front corneal surface irregularities to achieve the desired refractive outcome. This is particularly applicable in highly aberrated corneas, where wavefront aberrometry is often not possible. This article aims to review the recently published results
Marco Esposito et al.
European journal of oral implantology, 6(2), 169-179 (2013-08-09)
To compare the clinical effectiveness of two implant systems: Way Milano and Kentron (Geass, Pozzuolo del Friuli, UD, Italy). A total of 64 patients requiring at least two single crowns or partial fixed dental prostheses supported by a maximum of
Katarina Wolf et al.
The Journal of cell biology, 201(7), 1069-1084 (2013-06-27)
Cell migration through 3D tissue depends on a physicochemical balance between cell deformability and physical tissue constraints. Migration rates are further governed by the capacity to degrade ECM by proteolytic enzymes, particularly matrix metalloproteinases (MMPs), and integrin- and actomyosin-mediated mechanocoupling.
Emily Hams et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(1), 367-372 (2013-12-18)
Disease conditions associated with pulmonary fibrosis are progressive and have a poor long-term prognosis with irreversible changes in airway architecture leading to marked morbidity and mortalities. Using murine models we demonstrate a role for interleukin (IL)-25 in the generation of

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique