C0605

Z-Asp(O-Me)-Glu(O-Me)-Val-Asp(O-Me) fluoromethyl ketone

≥90% (HPLC)

• Synonyme(s) : Z-DEVD-FMK
• Formule empirique (notation de Hill) : C₃₀H₄₁N₄O₁₂F
• Numéro CAS: 210344-95-9
• Poids moléculaire : 668.66
• UNSPSC Code: 12352200
• PubChem Substance ID: 329774802
• MDL number: MFCD23380217
• Assay: ≥90% (HPLC)
• Form: powder

Propriétés

• assay: ≥90% (HPLC)
• form: powder
• color: off-white
• solubility: DMSO: ≥20 mg/mL, clear
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: COC(=O)CC[C@H](NC(=O)[C@H](CC(=O)OC)NC(=O)OCc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)OC)C(=O)CF
• InChI: 1S/C30H41FN4O12/c1-17(2)26(29(42)33-20(22(36)15-31)13-24(38)45-4)35-27(40)19(11-12-23(37)44-3)32-28(41)21(14-25(39)46-5)34-30(43)47-16-18-9-7-6-8-10-18/h6-10,17,19-21,26H,11-16H2,1-5H3,(H,32,41)(H,33,42)(H,34,43)(H,35,40)/t19-,20-,21-,26-/m0/s1
• InChI key: GBJVAVGBSGRRKN-JYEBCORGSA-N

Description

Biochem/physiol Actions

A cell-permeable inhibitor of caspase 3, 6, 7, 8, 10, which exhibits competitive and irreversible inhibition.

Features and Benefits

This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informations sur la sécurité

• Classe de stockage: 13 - Non Combustible Solids
• Que se passe-t-il ?: WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• EPI (équipement de protection individuelle): Eyeshields, Gloves, type N95 (US)