A7755

5α-Androstane-3α,17β-diol

• Synonyme(s) : 3α,17β-Dihydroxy-5α-androstane, Dihydroandrosterone
• Formule empirique (notation de Hill) : C₁₉H₃₂O₂
• Numéro CAS: 1852-53-5
• Poids moléculaire : 292.46
• NACRES: NA.77
• PubChem Substance ID: 24278236
• UNSPSC Code: 51111800
• EC Number: 217-447-4
• MDL number: MFCD00003676
• Assay: ≥98% (TLC)
• Form: powder

Propriétés

• assay: ≥98% (TLC)
• Quality Segment: 200
• form: powder
• drug control: USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada
• technique(s): toxicology assay: suitable
• solubility: methanol: 19.60-20.40 mg/mL, clear, colorless
• storage temp.: room temp
• SMILES string: [H][C@@]12CC[C@@]3([H])[C@]4([H])CC[C@H](O)[C@@]4(C)CC[C@]3([H])[C@@]1(C)CC[C@@H](O)C2
• InChI: 1S/C19H32O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12-17,20-21H,3-11H2,1-2H3/t12-,13+,14-,15-,16-,17-,18-,19-/m0/s1
• InChI key: CBMYJHIOYJEBSB-KHOSGYARSA-N
• Gene Information: rat ... Ar(24208)

Description

Application

5α-Androstane-3α,17β-diol (dihydroandrosterone) is a testosterone metabolite. Dihyroandrosterone inhibited the cell growth of seven cancer cell lines while showing weak toxicity on normal cell lines.

Biochem/physiol Actions

Dihydroandrosterone is a testosterone metabolite; affects sperm maturation and survival.

Informations sur la sécurité

• Pictogrammes: GHS08
• Mot-clé: Danger
• Codes de danger: H351,H360FD
• Mentions de précaution: P201 - P308 + P313
• Hazard Classifications: Carc. 2 - Repr. 1B
• Classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Que se passe-t-il ?: WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• EPI (équipement de protection individuelle): Eyeshields, Gloves, type N95 (US)