366927

Chloroforme

suitable for HPLC, ≥99.8%, contains 0.5-1.0% ethanol as stabilizer

• Synonyme(s) : Trichlorométhane, Trichlorure de méthylidyne
• Formule empirique (notation de Hill) : CHCl₃
• Numéro CAS: 67-66-3
• Poids moléculaire : 119.38
• Beilstein: 1731042
• Numéro MDL: MFCD00000826
• Code UNSPSC : 12190000
• ID de substance PubChem : 329755457
• Nomenclature NACRES : NA.04

Propriétés

• Qualité: HPLC grade
• Niveau de qualité: 100
• Densité de vapeur: 4.1 (vs air)
• Pression de vapeur: 160 mmHg ( 20 °C)
• Essai: ≥99.8%
• Forme: liquid
• Produit purifié par: glass distillation
• Contient: 0.5-1.0% ethanol as stabilizer
• Technique(s): HPLC: suitable
• Impuretés: Acetone and aldehyde, passes test; Acid and chloride, passes test; Free chlorine (Cl), passes test; H₂SO₄, passes test (darkened); ≤0.01% water
• Résidus d'évap.: <0.0003%
• Couleur: APHA: ≤10
• Indice de réfraction: n20/D 1.445 (lit.)
• pb: 60.5-61.5 °C (lit.)
• Pf: −63 °C (lit.)
• Densité: 1.48 g/mL at 25 °C; 1.492 g/mL at 25 °C (lit.)
• Traces de cations: Pb: ≤0.05 ppm
• λ: H₂O reference
• Absorption UV: λ: 245 nm A_max: 1.00; λ: 255 nm A_max: 0.15; λ: 260 nm A_max: 0.15; λ: 270 nm A_max: 0.02; λ: 290 nm A_max: 0.01; λ: 400 nm A_max: 0.01
• Adéquation: passes test for HPLC
• Température de stockage: room temp
• Chaîne SMILES: ClC(Cl)Cl
• InChI: 1S/CHCl3/c2-1(3)4/h1H
• Clé InChI: HEDRZPFGACZZDS-UHFFFAOYSA-N

Description

Application

• Novel Approaches for the Analysis and Isolation of Benzylisoquinoline Alkaloids in Chelidonium majus.: This study presents innovative methodologies using chloroform in the extraction and analysis processes, highlighting advances in alkaloid chemistry (Ganzera et al., 2024).


• Antioxidant, anti-amylase, anti-lipase, and efficiency of Satureja fatty acid on the anti-inflammatory parameters in lipopolysaccharide-stimulated macrophage through Nrf2/NF-kB/NADH oxidase pathway.: Although primarily focused on biological assays, this paper includes essential methodologies employing chloroform for the extraction and purification of biochemical compounds (Saharkhiz MJ et al., 2024).


• Recent additions and access to a multidimensional lipidomic database containing liquid chromatography, ion mobility spectrometry, and tandem mass spectrometry information.: Chloroform is utilized as a key solvent in the extraction and analysis processes within lipidomics, demonstrating its critical role in modern analytical techniques (Baker ES et al., 2024).


• Preparation and optimization of dummy molecularly imprinted polymer-based solid-phase extraction system for selective enrichment of p-toluene sulfonate esters genotoxic impurities.: The study includes the use of chloroform in the preparation of polymers for advanced chromatographic applications, illustrating its versatility in analytical methodologies (Shan G et al., 2024).

Conditionnement

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Informations sur la sécurité

• Pictogrammes: GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H302,H315,H319,H331,H336,H351,H361d,H372
• Conseils de prudence: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Classification des risques: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• Organes cibles: Central nervous system, Liver,Kidney
• Code de la classe de stockage: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): does not flash
• Point d'éclair (°C): does not flash