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Y0001547

1,2-propanediol

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

Propylène glycol

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About This Item

Formule linéaire :
CH3CH(OH)CH2OH
Numéro CAS:
Poids moléculaire :
76.09
Numéro Beilstein :
1340498
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Densité de vapeur

2.62 (vs air)

Pression de vapeur

0.08 mmHg ( 20 °C)

Famille d'API

propylene glycol

Température d'inflammation spontanée

779 °F

Limite d'explosivité

12.5 %

Fabricant/nom de marque

EDQM

Indice de réfraction

n20/D 1.432 (lit.)

Point d'ébullition

187 °C (lit.)

Pf

−60 °C (lit.)

Densité

1.036 g/mL at 25 °C (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

CC(O)CO

InChI

1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3

Clé InChI

DNIAPMSPPWPWGF-UHFFFAOYSA-N

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Propylene glycol EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

219.2 °F - closed cup

Point d'éclair (°C)

104 °C - closed cup


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Lot/Batch Number

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Consulter la Bibliothèque de documents

J S LaKind et al.
Critical reviews in toxicology, 29(4), 331-365 (1999-08-18)
The purpose of this article is to review and interpret the scientific literature on the mammalian toxicity of ethylene glycol (EG) and propylene glycol (PG), with the goal of comparing the toxicity of the two chemicals. This type of review
Janina Seubert et al.
PloS one, 9(5), e98347-e98347 (2014-05-31)
Scented cosmetic products are used across cultures as a way to favorably influence one's appearance. While crossmodal effects of odor valence on perceived attractiveness of facial features have been demonstrated experimentally, it is unknown whether they represent a phenomenon specific
J O Funk et al.
Contact dermatitis, 31(4), 236-241 (1994-10-01)
Evaluation of dermatitis associated with propylene glycol application or ingestion remains a challenge. The research dealing with skin reactions to propylene glycol is revisited and new aspects for future research are outlined. Based on literature review and our own observations
Li Wang et al.
Hepatology (Baltimore, Md.), 61(2), 486-496 (2014-09-10)
Defective autophagy is implicated in the pathogenesis of nonalcoholic fatty liver diseases (NAFLD) through poorly defined mechanisms. Cardiolipin is a mitochondrial phospholipid required for bioenergetics and mitophagy from yeast to mammals. Here we investigated a role for ALCAT1 in the
Holger Lessmann et al.
Contact dermatitis, 53(5), 247-259 (2005-11-15)
In the several publications reviewed in this article, propylene glycol (PG; 1,2-propylene glycol) is described as a very weak contact sensitizer, if at all. However, particular exposures to PG-containing products might be associated with an elevated risk of sensitization. To

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