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T1820004

Trapidil impurity B

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

3-AT

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About This Item

Formule empirique (notation de Hill):
C2H4N4
Numéro CAS:
61-82-5
Poids moléculaire :
84.08
Numéro Beilstein :
107687
Numéro MDL:
MFCD00005230
Code UNSPSC :
41116107
ID de substance PubChem :
329826690
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

trapidil

Fabricant/nom de marque

EDQM

Pf

150-153 °C (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

Nc1nc[nH]n1

InChI

1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)

Clé InChI

KLSJWNVTNUYHDU-UHFFFAOYSA-N

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Trapidil impurity B EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Pictogrammes

Health hazardEnvironment
GHS08,GHS09

Mention d'avertissement

Warning

Mentions de danger

H361d,H373,H411

Classification des risques

Aquatic Chronic 2 - Repr. 2 - STOT RE 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Matej Zábrady et al.
PloS one, 9(10), e109875-e109875 (2014-10-10)
With the growing availability of genomic sequence information, there is an increasing need for gene function analysis. Antibody-mediated "silencing" represents an intriguing alternative for the precise inhibition of a particular function of biomolecules. Here, we describe a method for selecting
Toni R Bartling et al.
Free radical biology & medicine, 74, 99-107 (2014-06-29)
Aberrant matrix metalloproteinase-1 (MMP-1) expression contributes to the pathogenesis of many degenerative disease processes that are associated with increased oxidative damage or stress. We and others have established that shifts in steady-state H2O2 production resulting from enforced antioxidant gene expression
Soumitra Sau et al.
PloS one, 9(7), e101294-e101294 (2014-07-09)
In the budding yeast, centromeres stay clustered near the spindle pole bodies (SPBs) through most of the cell cycle. This SPB-centromere proximity requires microtubules and functional kinetochores, which are protein complexes formed on the centromeres and capable of binding microtubules.
Benjamin Rothé et al.
Nucleic acids research, 42(16), 10731-10747 (2014-08-30)
Biogenesis of eukaryotic box C/D small nucleolar ribonucleoprotein particles (C/D snoRNPs) involves conserved trans-acting factors, which are proposed to facilitate the assembly of the core proteins Snu13p/15.5K, Nop58p/NOP58, Nop56p/NOP56 and Nop1p/Fibrillarin on box C/D small nucleolar RNAs (C/D snoRNAs). In
Young-Ok Son et al.
The Journal of biological chemistry, 289(41), 28660-28675 (2014-08-27)
The cadmium-transformed human lung bronchial epithelial BEAS-2B cells exhibit a property of apoptosis resistance as compared with normal non-transformed BEAS-2B cells. The level of basal reactive oxygen species (ROS) is extremely low in transformed cells in correlation with elevated expressions
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