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Key Documents

PHR1963

Supelco

(+)-Catechin

Pharmaceutical Secondary Standard; Certified Reference Material

Synonyme(s) :

(+)-Catechin, (+)-Cyanidanol, D-Catechin

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About This Item

Formule empirique (notation de Hill):
C15H14O6
Numéro CAS:
Poids moléculaire :
290.27
Numéro MDL:
Code UNSPSC :
41116107
Nomenclature NACRES :
NA.24

Qualité

certified reference material
pharmaceutical secondary standard

Niveau de qualité

Agence

traceable to USP 1096790

Famille d'API

catechins

CofA (certificat d'analyse)

current certificate can be downloaded

Conditionnement

pkg of 50 mg

Application(s)

pharmaceutical

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

O[C@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3

InChI

1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15+/m0/s1

Clé InChI

PFTAWBLQPZVEMU-DZGCQCFKSA-N

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Description générale

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

(+)-Catechin is a flavan-3-ol, that belongs to the family of polyphenolic flavonoids, called catechins. Found in green tea, it shows many health benefits, such as anti-oxidant, anti-inflammatory, anti-proliferative, and anti-platelet activity.

Application

This pharmaceutical secondary standard can also be used as follows:

  • Development of an ultra-high performance liquid chromatography-triple-quadrupole tandem mass spectrometry (UHPLC-MS-MS) method for the simultaneous determination of eight catechins and four theaflavins in three types of tea samples
  • Separation and estimation of six tea catechins and caffeine by an UHPLC method coupled to a UV detector from green tea samples
  • Simultaneous analysis of five naturally occurring catechins by an isocratic HPLC method
  • Infrared-assisted extraction (IRAE) followed by HPLC separation and quantification of catechin, epicatechin, and procyanidin B2 in grape seed samples
  • Analysis of caffeine and catechins from green tea leaves by pressurized liquid extraction (PLE) using ethyl lactate, water, and ethyl lactate + water mixtures

Remarque sur l'analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Note de bas de page

To see an example of a Certificate of Analysis for this material enter LRAC2624 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Produits recommandés

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pictogrammes

Exclamation mark

Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Study on infrared-assisted extraction coupled with high performance liquid chromatography (HPLC) for determination of catechin, epicatechin, and procyanidin B2 in grape seeds
Cai Y, et al.
Food Chemistry, 127, 1872-1877 (2011)
Pressurized liquid extraction of caffeine and catechins from green tea leaves using ethyl lactate, water and ethyl lactate+ water mixtures
Bermejo DV, et al.
Food and Bioproducts Processing, 96, 106-112 (2015)
Giftson J Senapathy et al.
Molecules (Basel, Switzerland), 25(21) (2020-10-28)
Worldwide, lung cancer remains one of the leading cancers with increasing mortality rates. Though chemotherapy for lung cancer is effective, it is always accompanied by unavoidable and grave side effects. Photodynamic therapy (PDT), using novel photosensitizers, is an advanced treatment

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