PHR1828

Eucalyptol

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonyme(s) : Eucalyptol, 1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octane, 1,8-Cineole, 1,8-Epoxy-p-menthane
• Formule empirique (notation de Hill): C₁₀H₁₈O
• Numéro CAS: 470-82-6
• Poids moléculaire : 154.25
• Numéro Beilstein : 105109
• Numéro CE : 207-431-5
• Numéro MDL: MFCD00167977
• Code UNSPSC : 12352212
• ID de substance PubChem : 329823628
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: certified reference material; pharmaceutical secondary standard
• Niveau de qualité: 300
• Agence: traceable to Ph. Eur. Y0000176; traceable to USP 1268900
• Famille d'API: cineole
• CofA (certificat d'analyse): current certificate can be downloaded
• Conditionnement: pkg of 500 mg
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Indice de réfraction: n20/D 1.457 (lit.)
• Point d'ébullition: 176-177 °C (lit.)
• Pf: 1-2 °C (lit.)
• Densité: 0.921 g/mL at 25 °C (lit.)
• Application(s): pharmaceutical (small molecule)
• Format: neat
• Température de stockage: 2-8°C
• Chaîne SMILES: C[C@]12CC[C@H](CC1)C(C)(C)O2
• InChI: 1S/C10H18O/c1-9(2)8-4-6-10(3,11-9)7-5-8/h8H,4-7H2,1-3H3/t8-,10+
• Clé InChI: WEEGYLXZBRQIMU-WAAGHKOSSA-N

Description

Description générale

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Eucalyptol, a natural monoterpene, is a component of many medicinally active aromatic plants, such as eucalyptus, cardamom, thyme, rosemary, and ginger. It exhibits subduing effect on mucus hypersecretion, non-purulent rhinosinusitis, and asthma.

Application

This pharmaceutical secondary standard can also be used as follows:

• Simultaneous estimation of menthol and eucalyptol in their combined marketed analgesic formulations by high-performance thin layer chromatography (HPTLC) procedure
• The development of an International Conference on Harmonization (ICH) guideline validated HPTLC method for the determination of α-pinene and eucalyptol in plants from the Lamiaceae family
• Headspace sorptive extraction (HSSE) of seven monoterpenes for their gas chromatography and mass spectrometry (GC-MS) based quantitative analysis from different honey samples
• Screening and estimation of eucalyptol in a polyherbal formulation using an HPTLC-based technique

Remarque sur l'analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Note de bas de page

To see an example of a Certificate of Analysis for this material enter LRAB9507 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Produits recommandés

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Informations sur la sécurité

• Pictogrammes: GHS02,GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H226,H317
• Conseils de prudence: P210 - P233 - P240 - P241 - P280 - P303 + P361 + P353
• Classification des risques: Flam. Liq. 3 - Skin Sens. 1
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): 125.6 °F - closed cup
• Point d'éclair (°C): 52 °C - closed cup