11709

Barbituric acid

for spectrophotometric det. of cyanide, ≥99.5%

• Synonyme(s) : 2,4,6-Trihydroxypyrimidine, Malonylurea
• Formule empirique (notation de Hill): C₄H₄N₂O₃
• Numéro CAS: 67-52-7
• Poids moléculaire : 128.09
• Numéro Beilstein : 120502
• Numéro CE : 200-658-0
• Numéro MDL: MFCD00006666
• Code UNSPSC : 12000000
• ID de substance PubChem : 329749535
• Nomenclature NACRES : NA.21

Propriétés

• Niveau de qualité: 100
• Pureté: ≥99.5% (HPLC); ≥99.5%
• Forme: solid
• Qualité: for spectrophotometric det. of cyanide
• Technique(s): UV/Vis spectroscopy: suitable
• Résidus de calcination: ≤0.05%
• Pf: 248-252 °C (dec.) (lit.)
• Traces d'anions: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤500 mg/kg
• Traces de cations: Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; Mg: ≤10 mg/kg; Mn: ≤5 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Zn: ≤5 mg/kg
• Chaîne SMILES: O=C1CC(=O)NC(=O)N1
• InChI: 1S/C4H4N2O3/c7-2-1-3(8)6-4(9)5-2/h1H2,(H2,5,6,7,8,9)
• Clé InChI: HNYOPLTXPVRDBG-UHFFFAOYSA-N

Description

Description générale

Barbituric acid is also known as malonurea or 6-hydroxyuracil, it is an odourless powder and is soluble in water. It has a very high pharmacological activity and can be used to synthesize addition derivatives of it, to be used in novel drug discovery. It basically acts on the central nervous system (CNS) depressants, thereby possessing a wide range from mild sedation to total anaesthesia.

Application

Barbituric acid with aromatic aldehydes was used in an experimental study, meant to demonstrate the increased efficiency of Knoevenagel condensation reaction for barbituric acid and various aromatic aldehydes on basic alumina, in the absence of organic solvents under microwave irradiation. It may also be used in electrochemical oxidation of iodine, using cyclic voltammetry and controlled-potential coulometry.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 302.0 °F - closed cup
• Point d'éclair (°C): 150.00 °C - closed cup
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)