MAB2076Z
Anti-Integrin β6 Antibody, clone CSβ6, azide free
clone CSbeta6, Chemicon®, from mouse
Synonyme(s) :
MAB2076
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About This Item
Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
Produits recommandés
Source biologique
mouse
Niveau de qualité
Forme d'anticorps
purified antibody
Type de produit anticorps
primary antibodies
Clone
CSbeta6, monoclonal
Espèces réactives
human, monkey, rat, rabbit
Ne doit pas réagir avec
mouse
Fabricant/nom de marque
Chemicon®
Technique(s)
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
Isotype
IgG1
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
wet ice
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
human ... ITGB6(3694)
mouse ... Itgb6(16420)
rat ... Itgb6(311061)
rhesus monkey ... Itgb6(700454)
Spécificité
Monoclonal antibody MAB2076Z, raised by immunizing beta6 knockout mice with recombinant secreted human alphavbeta6, is useful for flow cytometry and immunoprecipitation in all species tested, including mouse. It also works well for immunohistochemistry of acetone-fixed tissues in several species, including rat, rabbit, monkey, and human. The antibody does not work well for immunohistochemistry of mouse tissue. This antibody does not recognize the aV subunit and does not react with alphaV integrins other than alphavbeta6. Because the antibody is not effective in western blot, it is unknown whether the epitope recognized by the antibody localizes to the alphavbeta6 heterodimer or to the beta6 subunit only.
Immunogène
beta 6 knockout mice have been immunized with recombinant secreted human alpaVbeta6.
Application
Anti-Integrin β6 Antibody, clone CSβ6, azide free detects level of Integrin β6 & has been published & validated for use in FC, IP, IC, IH.
Immunohistochemistry (acetone fixation): Effective for Rabbit, rat, monkey, and human. Not effective for mouse tissue.
Immunocytochemistry: Effective for F6, HT-29, H441 cell lines (others not tested).
Flow cytometry: Effective for all species tested, including rabbit, rat, monkey, human, and mouse.
Immunoprecipitation
Optimal working dilutions must be determined by end user.
Immunocytochemistry: Effective for F6, HT-29, H441 cell lines (others not tested).
Flow cytometry: Effective for all species tested, including rabbit, rat, monkey, human, and mouse.
Immunoprecipitation
Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Integrins
Integrins
Forme physique
Format: Purified
Sterile-filtered liquid at 1 mg/mL in PBS, containing no preservatives.
Stockage et stabilité
Maintain at 2-8°C.
Autres remarques
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Informations légales
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
WGK 2
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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A continuous bovine kidney cell line constitutively expressing bovine ?v?6 integrin has increased susceptibility to foot-and-mouth disease virus.
LaRocco, M; Krug, PW; Kramer, E; Ahmed, Z; Pacheco, JM; Duque, H; Baxt, B; Rodriguez, LL
Journal of Clinical Microbiology null
A liposomal drug platform overrides peptide ligand targeting to a cancer biomarker, irrespective of ligand affinity or density.
Gray, BP; McGuire, MJ; Brown, KC
Testing null
Yahui Jiang et al.
Frontiers in oncology, 11, 690618-690618 (2021-10-09)
Implantation metastasis is the main means of dissemination in ovarian cancer. Our previous studies showed that SET and MYND domain-containing protein 3 (SMYD3) expression was higher in ovarian cancer spheroids than in monolayers. SMYD3 enhancement of spheroid invasion and adhesion
Novel ITGB6 variants cause hypoplastic-hypomineralized amelogenesis imperfecta and taurodontism: characterization of tooth phenotype and review of literature.
Sriwattanapong, et al.
BDJ open, 9, 15-15 (2023)
Theodore T Wing et al.
Reproduction (Cambridge, England), 159(4), 465-478 (2020-01-29)
Angiogenesis is fundamental to the expansion of the placental vasculature during pregnancy. Integrins are associated with vascular formation; and osteopontin is a candidate ligand for integrins to promote angiogenesis. Endothelial progenitor cells (EPCs) are released from bone marrow into the
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