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Merck
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Key Documents

DR1071

Sigma-Aldrich

Anti-TFAM Rabbit pAb

liquid, Calbiochem®

Synonyme(s) :

Anti-Transcription Factor A Mitochondrial

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

100

Forme d'anticorps

purified antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

liquid

Ne contient pas

preservative

Espèces réactives

mouse, human

Fabricant/nom de marque

Calbiochem®

Conditions de stockage

OK to freeze
avoid repeated freeze/thaw cycles

Isotype

IgG

Conditions d'expédition

wet ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... TFAM(7019)

Description générale

Purified rabbit polyclonal antibody. Recognizes the ~30 kDa TFAM protein.
Recognizes the ~30 kDa TFAM protein in mouse liver tissue.
This Anti-TFAM Rabbit pAb is validated for use in Immunoblotting for the detection of TFAM.

Immunogène

Full-length, human TFAM (aa 1-246)
Human

Application


Immunoblotting (1-5 g/ml)

Avertissement

Toxicity: Regulatory Review (Z)

Forme physique

In PBS, pH 7.13.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Remarque sur l'analyse

Negative Control
293T cells
Positive Control
Mouse liver tissue

Autres remarques

Variables associated with assay conditions will dictate the proper working dilution.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

nwg

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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J Matthew Hinkley et al.
Medicine and science in sports and exercise, 51(6), 1106-1115 (2019-01-11)
Doxorubicin (DOX) is a highly effective chemotherapeutic agent used in the treatment of a broad spectrum of cancers. However, clinical use of DOX is limited by irreversible and dose-dependent hepatotoxicity. The liver is the primary organ responsible for the clearance
Pieter A Leermakers et al.
BMC pulmonary medicine, 20(1), 20-20 (2020-01-23)
Both mitophagy, a selective mechanism for clearance of mitochondria, and mitochondrial biogenesis are key processes determining mitochondrial content and oxidative capacity of the musculature. Abnormalities in these processes could therefore contribute to deterioration of peripheral muscle oxidative capacity as observed
Wessel F Theeuwes et al.
Biochimica et biophysica acta. Molecular basis of disease, 1866(6), 165740-165740 (2020-02-23)
Physical inactivity contributes to muscle wasting and reductions in mitochondrial oxidative phenotype (OXPHEN), reducing physical performance and quality of life during aging and in chronic disease. Previously, it was shown that inactivation of glycogen synthase kinase (GSK)-3β stimulates muscle protein
Philippe Vangrieken et al.
PloS one, 16(1), e0245155-e0245155 (2021-01-13)
Impaired utero-placental perfusion is a well-known feature of early preeclampsia and is associated with placental hypoxia and oxidative stress. Although aberrations at the level of the mitochondrion have been implicated in PE pathophysiology, whether or not hypoxia-induced mitochondrial abnormalities contribute
Rosario Barone et al.
Journal of cellular physiology, 232(5), 1086-1094 (2016-08-04)
Conjugated linoleic acid (CLA) has been reported to improve muscle hypertrophy, steroidogenesis, physical activity, and endurance capacity in mice, although the molecular mechanisms of its actions are not completely understood. The aim of the present study was to identify whether
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