ABN38

Anti-RAB35 Antibody

from rabbit, purified by affinity chromatography

• Synonyme(s) : Ras-related protein Rab-35, GTP-binding protein RAY, Ras-related protein Rab-1C
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Produit purifié par: affinity chromatography
• Espèces réactives: rat, human, horse
• Réactivité de l'espèce (prédite par homologie): canine (based on 100% sequence homology), equine (based on 100% sequence homology)
• Technique(s): immunohistochemistry: suitable (paraffin); western blot: suitable
• Numéro d'accès NCBI: NP_006852
• Numéro d'accès UniProt: Q15286
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... RAB35(11021)

Description

Description générale

RAB35 is a member of the Rab GTPases identified in the human genome. It is ubiquitously expressed and regulates a fast endocytotic recycling events associated with the terminal steps of cytokinesis, the formation of immunological synapse, and peptide loading onto major histocompatibility complex III molecules. RAB35 also plays a significant role in the formation of the immunological synapse (IS) between peptide-loaded antigen presenting cells (APCs) and T cells.

Spécificité

This antibody recognizes RAB35 at the C-terminus.

Immunogène

KLH-conjugated linear peptide corresponding to the C-terminus of human RAB35.

Application

Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected RAB35 in normal human brain tissue.

This Anti-RAB35 Antibody is validated for use in WB, IH(P) for the detection of RAB35.

Qualité

Evaluated by Western Blot in human brain tissue lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected RAB35 on 10 µg of human brain tissue lysate.

Description de la cible

~19 kDa observed. The calculated molecular weight is 23 kDa

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable