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Merck
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AB5735

Sigma-Aldrich

Anti-Neurofilament M Antibody

Chemicon®, from chicken

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

chicken

Niveau de qualité

Forme d'anticorps

purified antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Espèces réactives

mouse, human, rat

Fabricant/nom de marque

Chemicon®

Technique(s)

immunocytochemistry: suitable
western blot: suitable

Numéro d'accès NCBI

Numéro d'accès UniProt

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... NEFM(4741)
mouse ... Nefm(18040)
rat ... Nefm(24588)

Spécificité

Neurofilament M (NF-M)

Immunogène

Recombinant C-terminal extension of rat NF-M, the so-called KE segment.

Application

Anti-Neurofilament M Antibody detects level of Neurofilament M & has been published & validated for use in WB & IC.
Research Category
Neuroscience
Research Sub Category
Neurofilament & Neuron Metabolism

Neuronal & Glial Markers
Western blot: 1:5,000-1:10,000

Immunocytochemistry: 1:1,000-1:2,000

Optimal working dilutions must be determined by the end user.

Forme physique

Chicken IgY. Liquid containing ~5 mM sodium azide.
Format: Purified

Stockage et stabilité

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids


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Consulter la Bibliothèque de documents

Víctor Hugo Cornejo et al.
Cell reports, 30(13), 4505-4517 (2020-04-03)
TRPM8 is the main ion channel responsible for cold transduction in the somatosensory system. Nerve terminal availability of TRPM8 determines cold sensitivity, but how axonal secretory organelles control channel delivery remains poorly understood. Here we examine the distribution of TRPM8
Niliksha Gunewardene et al.
Stem cells international, 2016, 1781202-1781202 (2016-03-12)
Induced pluripotent stem cells (iPSCs) may serve as an autologous source of replacement neurons in the injured cochlea, if they can be successfully differentiated and reconnected with residual elements in the damaged auditory system. Here, we explored the potential of
Rui O Costa et al.
Cell reports, 28(4), 864-876 (2019-07-25)
Ribosomes and a subset of cellular mRNAs are trafficked into axons of developing neurons. The axonal localization of translational machinery allows new proteins to be rapidly and locally synthesized during axonal growth and pathfinding. However, in mature neurons, axonal ribosomes
Karina Needham et al.
Stem cell research, 12(1), 241-249 (2013-11-28)
In severe cases of sensorineural hearing loss where the numbers of auditory neurons are significantly depleted, stem cell-derived neurons may provide a potential source of replacement cells. The success of such a therapy relies upon producing a population of functional
Carolina González et al.
Proceedings of the National Academy of Sciences of the United States of America, 113(7), 1823-1828 (2016-02-04)
The regulation of the axonal proteome is key to generate and maintain neural function. Fast and slow axoplasmic waves have been known for decades, but alternative mechanisms to control the abundance of axonal proteins based on local synthesis have also

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