345996
Glial Fibrillary Acidic Protein, Human Brain
Synonyme(s) :
GFAP
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About This Item
Code UNSPSC :
12352202
Produits recommandés
Pureté
≥90% (SDS-PAGE)
Niveau de qualité
Forme
lyophilized
Fabricant/nom de marque
Calbiochem®
Conditions de stockage
OK to freeze
Solubilité
distilled water: 1 mg/mL
Conditions d'expédition
ambient
Température de stockage
−20°C
Description générale
Native, glial fibrillary acidic protein purified from human brain. Main component of the intermediate filaments in astrocytes. Marker of sclerotic plaques in gliosed brain.
Native, glial fibrillary acidic protein purified from human brain. Marker of sclerotic plaques in brain and gliosed brain. Isolated from normal human brain. A component of astroglial intermediate filaments. Forms glial filaments in astrocytes in the central nervous system and in some Schwann cells in peripheral nerves.
Molecular Weight: 43,000-49,000
Molecular Weight: 43,000-49,000
Avertissement
Toxicity: Standard Handling (A)
Forme physique
Lyophilized from 16 mM Sodium Bicarbonate, pH 8.5.
Notes préparatoires
Prepared from tissues of individuals that have been shown by certified tests to be negative for HbsAg, HIV-1 and HIV-2 antibodies, HCV, and syphilis.
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Autres remarques
Anderiva, M., et al. 2001. Glia35, 189.
Masood, K., et al. 1993. J. Neurochem. 61, 160.
Liem, R.K., and Hutchison, S.B. 1982. Biochemistry21, 3221.
Dahl, D. 1973. Brain Res.57, 343.
Masood, K., et al. 1993. J. Neurochem. 61, 160.
Liem, R.K., and Hutchison, S.B. 1982. Biochemistry21, 3221.
Dahl, D. 1973. Brain Res.57, 343.
Informations légales
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
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Astrocytes become activated with certain infections, and this might alter the brain to trigger or worsen depressed mood. Indeed, astrocytes are chronically activated in people with HIV infection (PWH), who are much more frequently depressed than people without HIV (PWoH).
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PloS one, 8(8), e70019-e70019 (2013-08-13)
Lamotrigine trial in SPMS was a randomised control trial to assess whether partial blockade of sodium channels has a neuroprotective effect. The current study was an additional study to investigate the value of neurofilament (NfH) and other biomarkers in predicting
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
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