234405
Complement C5-Depleted Serum, Human
Synonyme(s) :
Complement Serum
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About This Item
Code UNSPSC :
12352202
Nomenclature NACRES :
NA.25
Produits recommandés
Forme
liquid
Fabricant/nom de marque
Calbiochem®
Conditions de stockage
OK to freeze
avoid repeated freeze/thaw cycles
Impuretés
C5 antigen, none detected (Ouchterlony)
Conditions d'expédition
dry ice
Température de stockage
−70°C
Description générale
Human serum depleted of complement component C5 by affinity chromatography.
Human serum that has been depleted of complement component C5 by affinity chromatography. Intended for the detection and quantitation of hemolytically active C5 complement component. The classical and alternative pathways are intact except for the specifically depleted component. Recommended assay volume: ≤60 µl
Actions biochimiques/physiologiques
Complement C5-depleted serum from humans produced by affinity chromatography aids the development of the complement cascade up to the desired convertase level. It eliminates the usual time-consuming, expensive, and stepwise formation of enzymatic complexes from purified products. Whole serum usage reduces the risk of protein inactivation during the process. It also promotes better physiological conditions. Complement C5-Depleted Serum is intended for the detection and quantitation of the hemolytically active C5 complement component. Creating complement convertases on erythrocytes enhances a better readout of the assay by spectrophotometric quantification of released hemoglobin.
Conditionnement
Please refer to vial label for lot-specific concentration.
Avertissement
Toxicity: Standard Handling (A)
Forme physique
In 145 mM NaCl, 10 mM sodium phosphate, pH 7.3.
Notes préparatoires
Prepared from plasma of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Reconstitution
Following initial thaw, aliquot and freeze (-70°C).
Informations légales
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
nwg
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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Les clients ont également consulté
Marcin Okroj et al.
PloS one, 7(10), e47245-e47245 (2012-10-17)
C3 and C5 convertases are central stages of the complement cascade since they converge the different initiation pathways, augment complement activation by an amplification loop and lead to a common terminal pathway resulting in the formation of the membrane attack
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