07-228

Anti-TACC2 Antibody

Upstate^®, from rabbit

• Synonyme(s) : transforming, acidic coiled-coil containing protein 2
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Produit purifié par: affinity chromatography
• Espèces réactives: human, mouse
• Réactivité de l'espèce (prédite par homologie): rat (based on 100% sequence homology)
• Fabricant/nom de marque: Upstate^®
• Technique(s): western blot: suitable
• Numéro d'accès NCBI: NP_996738
• Numéro d'accès UniProt: Q9JJG0
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... TACC2(10579)

Description

Description générale

TACC2, also known as transforming acidic coiled-coil-containing protein 2, belongs to the transforming acidic coiled-coil-containing (TACC) protein family. This group of proteins is defined by its highly conserved coiled-coil domain. This domain is necessary for the assignment of the centrosome-spindle apparatus during cell cycling. There are three proteins belonging to the TACC family; TACC1, TACC2, and TACC3. TACC2 has been reported as playing a necessary role in cultured cell microtubule stabilization. It has also been shown that the binding of TACC2 by T antigen can cause chromosomal instability and mitotic defects (Tei, 2009). Research into the over expression of TACC2 strongly suggests a potential function as a tumor suppressor (Tei, 2009).

Immunogène

KLH-conjugated linear peptide corresponding to the mature chain of mouse TACC2.

Application

Anti-TACC2 Antibody is a Rabbit Polyclonal Antibody for detection of TACC2 also known as transforming acidic coiled-coil containing protein 2 & has been validated in WB.

Qualité

Evaluated by Western Blot in mouse testis tissue lysate.

Western Blot Analysis: 2 µg/mL of this antibody detected TACC2 on 10 µg of mouse testis tissue lysate.

Description de la cible

Observed molecular weight, 73 kDa
Note this protein can be highly modified and several isoforms exist.

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable