The extinction coefficient is not determined or reported for this product. Concentration is measured by determining total protein content through quantitative amino acid analysis. Data is provided in the Certificate of Analysis for HPLC-UV-MS analysis, but direct spectrophotometric analysis is not performed.
A-166
Adalimumab solution
10.0 mg/mL (12.5 mM Histidine Buffer), certified reference material, Cerilliant®
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About This Item
Le tarif et la disponibilité ne sont pas disponibles actuellement.
Produits recommandés
Qualité
certified reference material
Niveau de qualité
Forme
liquid
Caractéristiques
Snap-N-Spike®/Snap-N-Shoot®
Conditionnement
ampule of 0.25 mL
Fabricant/nom de marque
Cerilliant®
Concentration
10.0 mg/mL (12.5 mM Histidine Buffer)
Technique(s)
liquid chromatography (LC): suitable
Application(s)
clinical testing
Format
single component solution
Température de stockage
−20°C
Description générale
Adalumimab is a therapeutic monoclonal antibody used for the treatment of psoriasis, rheumatoid arthritis, and Crohn′s disease. Adalimumab (Humira) in solution is a primary certified reference material of the recombinantly expressed and purified therapeutic monoclonal antibody (mAb). The product is traceable to higher order standards from National Institute of Standards and Technology (NIST) through an unbroken chain of comparisons. It satisfies the criterion for certified reference material and primary standard categories according to the ISO requirements. The solution contains not less than 0.25 mL of approximately 10 mg/ml certified solution. The manufacturing process follows the quality control standards, ISO 17034, ISO/IEC 17025, and ISO 9001.
Application
Adalimumab (Humira) solution has been used to determine the metrological traceability for adalimumab (ADL).[1] It is also suitable for in vitro applications such as identification, calibration, and quantification of analytes in analytical and R&D settings.
Caractéristiques et avantages
- Adalimumab (Humira) content is quantitatively measured by amino acid analysis (AAA).
- Every raw material employed has been identified and comprehensively characterized using a variety of analytical methods.
- The fill volume is gravimetrically verified at various stages during the dispensing process using qualified and calibrated balances.
- Long-term stability has been evaluated under freezer storage conditions (-10 °C to -25 °C).
Notes préparatoires
- Thaw the product in a refrigerator or at room temperature and ensure thorough mixing before use.
- Avoid refreezing the product once thawed.
- When spiking into a matrix or diluting to required concentrations, it is recommended to quantitatively transfer the appropriate volume using established laboratory practices.
Autres remarques
This product′s purpose is for testing. THIS PRODUCT IS NOT INTENDED FOR HUMAN OR THERAPEUTIC USE. For comprehensive details regarding the nature of any hazards and recommended precautions, kindly refer the safety data sheet.
Informations légales
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Produit(s) apparenté(s)
Réf. du produit
Description
Tarif
Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
WGK 2
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
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Certificats d'analyse (COA)
Lot/Batch Number
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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Quantification of infliximab and adalimumab in human plasma by a liquid chromatography tandem mass spectrometry kit and comparison with two ELISA methods
Tron C, et al.
Bioanalysis, 14(11), 831-844 (2022)
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What is the extinction coefficient of this CRM?
1 answer-
Helpful?
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What is the approximate concentration of adalimumab (humira) in A-166?
1 answer-
The target concentration of this standard is 10 mg/mL. The actual concentration is reported on the lot-specific Certificate of Analysis. See the link below for a sample COA:
https://www.cerilliant.com/shopOnline/COA.aspx?itemno=ceebedfd-7433-411d-8f61-5e06225f4e1d&lotno=FN04112201Helpful?
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