Accéder au contenu
Merck
Toutes les photos(2)

Documents

D0387

Sigma-Aldrich

6,7-Dimethyl-5,6,7,8-tetrahydropterine hydrochloride

≥95%

Synonyme(s) :

2-Amino-6,7-dimethyl-4-hydroxy-5,6,7,8-tetrahydropteridine, DMPH4

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
Toutes les photos(2)

About This Item

Formule empirique (notation de Hill):
C8H13N5O · HCl
Numéro CAS:
945-43-7
Poids moléculaire :
231.68
Numéro MDL:
MFCD00012731
Code UNSPSC :
12352100
ID de substance PubChem :
57654058
Nomenclature NACRES :
NA.22

Niveau de qualité

100

Pureté

≥95%

Forme

powder

Température de stockage

−20°C

Chaîne SMILES 

Cl[H].CC1Nc2nc(N)nc(O)c2NC1C

InChI

1S/C8H13N5O.ClH/c1-3-4(2)11-6-5(10-3)7(14)13-8(9)12-6;/h3-4,10H,1-2H3,(H4,9,11,12,13,14);1H

Clé InChI

GIHYTRGUZVYCQX-UHFFFAOYSA-N

Catégories apparentées

Actions biochimiques/physiologiques

Synthetic reduced pterin cofactor for nitric oxide synthetase, and for phenylalanine, tyrosine, and tryptophan hydroxylases; less active than the natural cofactor, tetrahydrobiopterin (BH4).

Pictogrammes

CorrosionExclamation mark
GHS05,GHS07

Mention d'avertissement

Danger

Mentions de danger

H315,H318,H335

Classification des risques

Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Les clients ont également consulté

Slide 1 of 5

1 of 5

5-Hydroxy-L-tryptophan powder

Sigma-Aldrich

H9772

5-Hydroxy-L-tryptophan

L-Tyrosine BioUltra, ≥99.0% (NT)

Sigma-Aldrich

93829

L-Tyrosine

Catalase from bovine liver aqueous suspension, 40,000-60,000 units/mg protein (E1%/405)

Sigma-Aldrich

C100

Catalase from bovine liver

4-Aminopyridine ≥99%

Sigma-Aldrich

275875

4-Aminopyridine

Sodium periodate ACS reagent, ≥99.8%

Sigma-Aldrich

311448

Sodium periodate

V S Kudrin et al.
Biulleten' eksperimental'noi biologii i meditsiny, 91(5), 553-554 (1981-05-01)
Activity and KM of hypothalamic tyrosine hydroxylase (TH) were studied in rats preliminarily tested for predisposition to high ethanol consumption. It was shown that as regards cofactor of DMPH4 enzymatic reaction, KM of hypothalamic TH of animals with an initially
Ryotaro Hara et al.
AMB Express, 3(1), 70-70 (2013-12-11)
5-Hydroxy-l-tryptophan (5-HTP) is a naturally occurring aromatic amino acid present in the seeds of the African plant Griffonia simplicifolia. Although 5-HTP has therapeutic effects in various symptoms, efficient method of producing 5-HTP has not been established. In this study, we
I Jennings et al.
The Journal of biological chemistry, 265(4), 1885-1889 (1990-02-05)
BALB/c mice were immunized with a synthetic co-factor of the aromatic amino acid hydroxylases, 6,7-dimethyl-5,6,7,8-tetrahydropterin, conjugated to albumin. Hybridoma cell lines isolated from the immunized mice secreted monoclonal antibodies reacting specifically with the pterin molecule and monoclonal antibodies which were
Reid M McCarty et al.
Biochemistry, 48(11), 2301-2303 (2009-02-24)
To elucidate the early steps required during biosynthesis of a broad class of 7-deazapurine-containing natural products, we have studied the reaction catalyzed by Escherichia coli QueD, a 6-pyruvoyl-5,6,7,8-tetrahydropterin synthase (PTPS) homologue possibly involved in queuosine biosynthesis. While mammalian PTPS homologues
I G Jennings et al.
Proceedings of the National Academy of Sciences of the United States of America, 88(13), 5734-5738 (1991-07-01)
A monoclonal anti-idiotype antibody, NS7, previously shown to mimic the binding of the pterin cofactor of phenylalanine hydroxylase (phenylalanine 4-monooxygenase, EC 1.14.16.1) has been used to localize the cofactor binding site within the phenylalanine hydroxylase catalytic domain to a 27-amino-acid
Afficher tous les articles scientifiques apparentés

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique