901332

Polyester bis-MPA dendron 8 NHBoc, 1 azide (core)

generation 3

• Synonyme(s) : Bis-MPA dendron, PFd-G3-Azide-NH-BOC
• Formule empirique (notation de Hill): C₁₀₅H₁₇₃N₁₁O₄₆
• Poids moléculaire : 2325.54
• Code UNSPSC : 12352125
• Nomenclature NACRES : NA.23

Propriétés

• Description: 8 NHBoc, 1 azide (core)
• Niveau de qualité: 100
• Forme: solid
• Poids mol.: generation 3
• Nb de groupes de surface: 8
• Couleur: white to off-white
• Groupe fonctionnel: azide (core)
• Température de stockage: −20°C

Description

Description générale

• Polymer architecture: Dendron
• End Group Functionality: Boc-protected amine
• Boc : tert-Butyloxycarbonyl
• Bis-MPA : 2,2-Bis(hydroxymethyl)propionic acid.

Application

Bis-MPA (or 2,2-Bis(methylol)propionic acid) is an aliphatic, pro-chiral molecule comprised of two hydroxyls and one carboxylic group that has been used in the synthesis of many different types of polymers. Dendrons synthesized from bis-MPA are biodegradable and have low cytotoxicity, making them well suited for use in biological research applications. These materials have been used in many applications such as signal amplification in bioassays and in drug delivery applications. After Boc deprotection, amine-functionalized dendrons can be readily used in EDC or DCC coupling reactions with carbonyl-containing compounds to yield highly functionalized materials for a variety of biomedical applications. Additionally, the azide-core can be readily conjugated using either copper(I)-catalysed alkyne-azide cycloaddition (CuAAC) or strain-promoted alkyne-azide cycloaddition (SPAAC).

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable