730971
2-(Diisopropylamino)ethyl methacrylate
97%, contains ~100 ppm monomethyl ether hydroquinone as inhibitor
Synonyme(s) :
DPA, DPAEMA
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About This Item
Formule empirique (notation de Hill):
C12H23NO2
Numéro CAS:
Poids moléculaire :
213.32
Numéro CE :
Numéro MDL:
Code UNSPSC :
12162002
ID de substance PubChem :
Nomenclature NACRES :
NA.23
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Pureté
97%
Forme
liquid
Contient
~100 ppm monomethyl ether hydroquinone as inhibitor
Indice de réfraction
n20/D 1.145
Densité
0.900 g/mL at 25 °C
Température de stockage
2-8°C
Chaîne SMILES
CC(C)N(CCOC(=O)C(C)=C)C(C)C
InChI
1S/C12H23NO2/c1-9(2)12(14)15-8-7-13(10(3)4)11(5)6/h10-11H,1,7-8H2,2-6H3
Clé InChI
SVYHMICYJHWXIN-UHFFFAOYSA-N
Description générale
2-(Diisopropylamino)ethyl methacrylate (DPA) is a methacrylate class of monomer used to prepare various DPA-derived polymers, which includes poly(2-(diisopropylamino)ethyl methacrylate) (PDPA). PDPA is a water-soluble polymer, which exhibits sensitivity to changes in pH and temperature. At pH levels below its pKa value of approximately 6.5, PDPA undergoes a transition from hydrophobic to hydrophilic behavior. This transition is attributed to the protonation of its amino groups. These unique properties of PDPA polymers consequently make them very useful in various applications such as drug delivery, gene delivery, sensors, surfaces, membranes, and chromatography.
Application
2-(Diisopropylamino)ethyl methacrylate can be used:
- As a monomer in the synthesis of multi-responsive hyperbranched copolymers by combining poly(oligo(ethylene glycol)methyl methacrylate) (P(OEGMA)) and 2-(diisopropylamino)ethyl methacrylate (PDIPAEMA) using RAFT polymerization. These polymers find application in drug delivery, gene delivery and tissue engineering.
- A monomers in the synthesis of block copolymer poly(ethyleneglycol)-b-poly(2-(diisopropylamino)ethyl methacrylate) (PEG-b-PDPAEMA). These pH-responsive micelles can be used for enhanced intracellular drug delivery. The DPA monomer contributes to the pH-responsive nature of the copolymers.
Mention d'avertissement
Danger
Mentions de danger
Conseils de prudence
Classification des risques
Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
Organes cibles
Respiratory system
Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
210.0 °F
Point d'éclair (°C)
98.9 °C
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