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275247

Sigma-Aldrich

4-(2-Aminoethyl)benzenesulfonamide

99%

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About This Item

Formule linéaire :
H2NCH2CH2C6H4SO2NH2
Numéro CAS:
35303-76-5
Poids moléculaire :
200.26
Numéro CE :
252-501-0
Numéro MDL:
MFCD00010301
Code UNSPSC :
12352100
ID de substance PubChem :
24856636
Nomenclature NACRES :
NA.22

Pureté

99%

Forme

powder

Pf

150-152 °C (lit.)

Chaîne SMILES 

NCCc1ccc(cc1)S(N)(=O)=O

InChI

1S/C8H12N2O2S/c9-6-5-7-1-3-8(4-2-7)13(10,11)12/h1-4H,5-6,9H2,(H2,10,11,12)

Clé InChI

FXNSVEQMUYPYJS-UHFFFAOYSA-N

Informations sur le gène

human ... CA1(759) , CA2(760) , CA5A(763) , CA5B(11238) , CA9(768)
mouse ... Car13(71934) , Car5a(12352)

Description générale

The human hepatocellular carcinoma (HCC) cells were treated with its inhibitor 4-(2-aminoethyl)benzenesulfonamide.

Application

4-(2-Aminoethyl)benzenesulfonamide was used to develop a model system to study the implementation of a microfluid chip required for Fourier transform measurements of biochemical interactions.

Pictogrammes

Corrosion
GHS05

Mention d'avertissement

Warning

Mentions de danger

H290,H315,H319

Classification des risques

Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2

Code de la classe de stockage

8A - Combustible corrosive hazardous materials

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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C H Mastrangelo et al.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 2010, 5318-5321 (2010-11-26)
New developments in microfluidic chip technology enable the construction of chemical spectrum analyzers that can probe the binding interactions between chemical entities. In this paper we report the implementation of a microfluidic chip suitable for Fourier transform measurements of biochemical
P Megyeri et al.
Immunology, 86(4), 629-635 (1995-12-01)
Monocytes freshly isolated from human blood produced large amounts of superoxide when triggered by phorbol ester. After monocytes were cultured for 18-24 hr in endotoxin-free, non-adherent conditions, they produced low amounts of superoxide. Addition of lipopolysaccharide (LPS), interferon-gamma (IFN-gamma), tumour
Su-jong Yu et al.
Acta pharmacologica Sinica, 32(7), 912-920 (2011-06-15)
The hypoxic condition within large or infiltrative hypovascular tumors produces intracellular acidification, which could activate many signaling pathways and augment cancer cell growth and invasion. Carbonic anhydrase-IX (CA-IX) is an enzyme lowering pH. This study is to examine whether hypoxia
Layne D Williams et al.
Analytical chemistry, 82(14), 6025-6031 (2010-06-24)
Surface plasmon resonance (SPR) is a popular technique for label-free detection of biomolecular interactions at a surface. SPR yields quantitative kinetic association and dissociation constants of surface interactions such as the binding of two molecular species, one present in the
Gayan S Jayawickrama et al.
PloS one, 13(4), e0196404-e0196404 (2018-04-25)
The mammalian kynurenine aminotransferase (KAT) enzymes are a family of related isoforms that are pyridoxal 5'-phosphate-dependent, responsible for the irreversible transamination of kynurenine to kynurenic acid. Kynurenic acid is implicated in human diseases such as schizophrenia where it is found
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