Skip to Content
Merck
All Photos(4)

Key Documents

View All Documentation

N7627

Sigma-Aldrich

L-Norvaline

≥99% (TLC)

Synonym(s):

(S)-(+)-2-Aminopentanoic acid, (S)-2-Aminovaleric acid

Sign Into View Organizational & Contract Pricing
All Photos(4)

About This Item

Linear Formula:
CH3CH2CH2CH(NH2)CO2H
CAS Number:
6600-40-4
Molecular Weight:
117.15
Beilstein:
1721162
EC Number:
229-543-3
MDL number:
MFCD00064421
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24897833
NACRES:
NA.26

Product Name

L-Norvaline, arginase inhibitor

Quality Level

200

Assay

≥99% (TLC)

form

powder

color

white

mp

>300 °C (lit.)

application(s)

detection

SMILES string

CCC[C@H](N)C(O)=O

InChI

1S/C5H11NO2/c1-2-3-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1

InChI key

SNDPXSYFESPGGJ-BYPYZUCNSA-N

Looking for similar products? Visit Product Comparison Guide

Application


  • Nanodrugs mediate TAMs-related arginine metabolism interference to boost photodynamic immunotherapy.: This study explores the use of nanodrugs to interfere with arginine metabolism in tumor-associated macrophages (TAMs), enhancing the efficacy of photodynamic immunotherapy. L-Norvaline plays a crucial role in this metabolic interference (Chen et al., 2024).

Biochem/physiol Actions

L-Norvaline enhances NO production from activated macrophages.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000400300
0000372977
0000360790
0000325254
0000400300

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

C I Chang et al.
The American journal of physiology, 274(1 Pt 2), H342-H348 (1998-02-12)
In macrophages and many other cell types, L-arginine is used as a substrate by both nitric oxide synthase (NOS) and arginase to produce nitric oxide (NO) and urea, respectively. Because the availability of L-arginine is a major determinant for NO
Seyed Abdollah Hosseini et al.
International journal of molecular sciences, 20(4) (2019-03-01)
The importance of magnesium (Mg) for plant growth is well-documented. Silicon (Si)-mediated alleviation of mineral deficiencies has been also reported in a number of plant species; however, there is no report on the relevance of Si nutrition in plants grown
Nelson Machado et al.
Journal of the science of food and agriculture, 97(13), 4295-4305 (2017-03-10)
Freezing represents a common conservation practice regarding vegetal foodstuffs. Since compositional features need to be monitored during storage, the development of rapid monitoring tools suitable for assessing nutritional characteristics arises as a pertinent issue. In this study, cowpea (Vigna unguiculata
Ying-Chen Lin et al.
The New phytologist, 223(4), 1904-1917 (2019-05-16)
Choline kinase catalyzes the initial reaction step of choline metabolism that produces phosphocholine, a prerequisite for the biosynthesis of a primary phospholipid phosphatidylcholine. However, the primary choline kinase and its role in plant growth remained elusive in seed plants. Here
Megan L Matthews et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(42), 17723-17728 (2009-10-10)
The alpha-ketoglutarate-dependent hydroxylases and halogenases employ similar reaction mechanisms involving hydrogen-abstracting Fe(IV)-oxo (ferryl) intermediates. In the halogenases, the carboxylate residue from the His(2)(Asp/Glu)(1) "facial triad" of iron ligands found in the hydroxylases is replaced by alanine, and a halide ion
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service