N7127
DL-Normetanephrine hydrochloride
≥98%
Synonym(s):
DL-α-(Aminomethyl)-4-hydroxy-3-methoxybenzenemethanol hydrochloride
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About This Item
Empirical Formula (Hill Notation):
C9H13NO3 · HCl
CAS Number:
Molecular Weight:
219.67
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Recommended Products
Quality Level
Assay
≥98%
form
powder
solubility
H2O: 50 mg/mL
SMILES string
NCC(C1=CC(OC)=C(C=C1)O)O.Cl
InChI
1S/C9H13NO3.ClH/c1-13-9-4-6(8(12)5-10)2-3-7(9)11;/h2-4,8,11-12H,5,10H2,1H3;1H
InChI key
VKFPRGQZWKTEON-UHFFFAOYSA-N
Biochem/physiol Actions
Norepinephrine metabolite.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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G Eisenhofer
Naunyn-Schmiedeberg's archives of pharmacology, 349(3), 259-269 (1994-03-01)
The importance of neuronal reuptake for terminating the actions of noradrenaline is well established, but the role of extraneuronal uptake is less clear. This study used plasma concentrations of the extraneuronal noradrenaline metabolite, normetanephrine, to estimate rates of extraneuronal removal
M Tsunoda et al.
Analytical biochemistry, 269(2), 386-392 (1999-05-01)
A highly specific and sensitive automated high-performance liquid chromatographic method for the simultaneous determination of catecholamines (CAs; norepinephrine, epinephrine, and dopamine) and their 3-O-methyl metabolites (normetanephrine, metanephrine, and 3-methoxytyramine) is described. Automated precolumn ion-exchange extraction of diluted plasma is coupled
Jiamin Zheng et al.
Analytica chimica acta, 1037, 159-167 (2018-10-08)
A robust, sensitive, high-throughput method for the detection and quantification of catecholamines in serum, including dopamine, 5-methoxytryptamine, tyramine, phenylethylamine (PEA), epinephrine (EPI), norepinephrine (NE), metanephrine (MN), and normetanephrine (NMN) is described. It is based on liquid chromatography-tandem mass spectrometry (LC-MS/MS)
T Mano et al.
Thyroid : official journal of the American Thyroid Association, 8(4), 353-358 (1998-05-20)
Clinical and experimental data suggest that thyroid hormone affects the actions of catecholamine (CA). However, the serum or tissue levels of CA during thyroid disorders have not been well defined. Accordingly, we investigated the levels of CA and their metabolites
Riin Rebane et al.
European journal of mass spectrometry (Chichester, England), 26(1), 46-54 (2019-07-11)
Metanephrine and normetanephrine are measured in blood plasma to diagnose different diseases. Simpler sample preparation procedures are preferred but tend to yield less purified extracts. Therefore, thorough investigation of matrix effects is required. In this work, several sample preparation methods
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