Skip to Content
Merck
All Photos(1)

Key Documents

M3903

Sigma-Aldrich

Methoxypolyethylene glycol p-nitrophenyl carbonate

average mol wt 5,000

Synonym(s):

Methoxy PEG Nitrophenyl Carbonate, Methoxypoly(ethylene glycol) nitrophenyl carbonate, Polyethylene glycol, mPEG-NPC

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

MDL number:
MFCD00131597
UNSPSC Code:
12161900
NACRES:
NA.25

mol wt

average mol wt 5,000

Quality Level

300

storage temp.

−20°C

General description

Methoxypolyethylene glycol p-nitrophenyl carbonate is a polyethylene glycol (PEG) derivative. PEGs are widely used as a covalent modifier of biologic macromolecules and particulates and for mechanism of drug delivery.

Application

Methoxypolyethylene glycol p-nitrophenyl carbonate has been used in a study to obtain unimolecular dendritic micelles designed as solubility enhancers. It has also been used in a study to investigate the properties of lipase from Candida rugosa modified with Mpeg. It is also useful for modification of proteins.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
SLCP9186
SLCM3031
070M5012V
070M5012
SLBX9668

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Hu Yang et al.
Journal of colloid and interface science, 273(1), 148-154 (2004-03-31)
Unimolecular dendritic micelles designed as solubility enhancers were obtained by coupling polyethylene glycol (PEG) to Starburst polyamidoamine (PAMAM) dendrimers. Micelles-750, -2000, and -5000 have a generation 3.0 dendrimer core (32 primary amine end groups) and PEG arms with molecular weights
Properties of methoxy(polyethylene glycol)-lipase from Candida rugosa in organic solvents
Zacchigna, M., et al.
Il Farmaco Ed. Sc., 53, 758-758 (1998)
F M Veronese et al.
Applied biochemistry and biotechnology, 11(2), 141-152 (1985-04-01)
A single-step method of activation of monomethoxypolyethylene glycols suitable for its binding to polypeptides and proteins is proposed. Based on the reaction with 2,4,5-trichlorophenylchloroformate or p-nitrophenylchloroformate, it gives reactive PEG-phenylcarbonate derivatives. The PEG intermediate is stable on storage, the activating
Chemistry of polyethylene glycol conjugates with biologically active molecules
Zalipsky, S., et al.
Advanced Drug Delivery Reviews, 16, 157-157 (1995)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service