46985
Fluorescein-5-thiosemicarbazide
suitable for fluorescence, ~80% (HPCE)
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About This Item
Empirical Formula (Hill Notation):
C21H15N3O5S
CAS Number:
Molecular Weight:
421.43
MDL number:
UNSPSC Code:
12352125
PubChem Substance ID:
NACRES:
NA.32
Recommended Products
Assay
~80% (HPCE)
Quality Level
form
solid
solubility
DMF: soluble
H2O: soluble
fluorescence
λex 492 nm; λem 516 nm in 0.1 M Tris pH 9.0
suitability
suitable for fluorescence
storage temp.
−20°C
SMILES string
NNC(=S)Nc1ccc(c(c1)C(O)=O)C2=C3C=CC(=O)C=C3Oc4cc(O)ccc24
InChI
1S/C21H15N3O5S/c22-24-21(30)23-10-1-4-13(16(7-10)20(27)28)19-14-5-2-11(25)8-17(14)29-18-9-12(26)3-6-15(18)19/h1-9,25H,22H2,(H,27,28)(H2,23,24,30)
InChI key
MEUCHQDLZYLNQY-UHFFFAOYSA-N
Related Categories
General description
Fluorescein-5-thiosemicarbazide, also known as FTC, is a fluorescent probe. The FTSC fluorescent spectra is like FITC, a preferred fluorescent tag for proteomics. The fluorescence spectral properties of FTSC-labeled vesicles obtained by reductive amination are fully compatible with the argon laser of fluorescent instruments.
Application
Fluorescein-5-thiosemicarbazide can be used as a fluorescent labeling reagent to label:
- Cell-surface functional groups (glycophorins) in the study of the effect of deoxygenation in the red blood cell membrane.
- Saccharides applicable in polysaccharide imaging in live cells.
- Chondroitin sulfate nanogels applicable in cell-specific drug delivery applications.
Features and Benefits
Fluorescein-5-thiosemicarbazide has the following benefits -
- It displays strong fluorescence property.
- Shows an intrinsic reactivity of the thiosemicarbazide group towards the aldehyde group.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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