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Key Documents

H0100100

Haloperidol decanoate

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Decanoic acid 4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidinyl ester

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About This Item

Empirical Formula (Hill Notation):
C31H41ClFNO3
CAS Number:
Molecular Weight:
530.11
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

haloperidol

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C31H41ClFNO3/c1-2-3-4-5-6-7-8-11-30(36)37-31(26-14-16-27(32)17-15-26)20-23-34(24-21-31)22-9-10-29(35)25-12-18-28(33)19-13-25/h12-19H,2-11,20-24H2,1H3

InChI key

GUTXTARXLVFHDK-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Haloperidol decanoate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

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Ira D Glick et al.
The Journal of clinical psychiatry, 66(5), 638-641 (2005-05-14)
To compare the long-term efficacy and tolerability of oral quetiapine with those of intramuscular haloperidol. Patients with DSM-IV-diagnosed schizophrenia or schizoaffective disorder requiring long-term antipsychotic treatment were randomly assigned to open-label oral quetiapine or intramuscular haloperidol decanoate for 48 weeks.
Long term results of unilateral posteroventral pallidotomy for antipsychotic drug induced tardive dyskinesia.
M W P M Lenders et al.
Journal of neurology, neurosurgery, and psychiatry, 76(7), 1039-1039 (2005-06-21)
[Psychiatric care for patients with addiction of amphetamine, CNS stimulant].
Tetsuji Kubakawa et al.
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 111(7), 850-853 (2009-12-17)
Reversible cerebral atrophy: a case report and literature review.
Uma Thirugnanasampanthan et al.
General hospital psychiatry, 28(5), 458-462 (2006-09-05)
Delphine Charvin et al.
Neurobiology of disease, 29(1), 22-29 (2007-10-02)
Huntington's disease (HD) results from an abnormal polyglutamine extension in the N-terminal region of the huntingtin protein. This mutation causes preferential degeneration of striatal projection neurons. We previously demonstrated, in vitro, that dopaminergic D2 receptor stimulation acted synergistically with mutated

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