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Zilpaterol hydrochloride

VETRANAL®, analytical standard

Synonym(s):

(6RS,7RS)-4,5,6, 7-Tetrahydro-7-hydroxy-6-[(1-methylethyl)amino]imidazo[ 4,5,1-jk][1]benzazepin-2(1H)-one hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C14H19N3O2 · HCl
CAS Number:
Molecular Weight:
297.78
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
veterinary

format

neat

storage temp.

2-8°C

SMILES string

Cl.[n]21c3c(nc2O)cccc3[C@H]([C@@H](CC1)NC(C)C)O

InChI

1S/C14H19N3O2.ClH/c1-8(2)15-11-6-7-17-12-9(13(11)18)4-3-5-10(12)16-14(17)19;/h3-5,8,11,13,15,18H,6-7H2,1-2H3,(H,16,19);1H/t11-,13-;/m1./s1

InChI key

GIEFXLLRTJNFGT-LOCPCMAASA-N

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General description

Zilpaterol belongs to the group of β-adrenergic agonists, used in the treatment of lung diseases due to its brochodilating nature. It is also widely used in veterinary medicine as a growth promoter for increasing muscle gain and decreasing fat.

Application

Zilpaterol hydrochloride analytical standard can be used as follows:
  • Determination of zilpaterol in cattle plasma and tissue samples using solid phase extraction (SPE) well plate of 96 samples for sample preparation and subsequent analysis by liquid chromatography-triple quadrupole mass spectrometry (LC-MS/MS)
  • Multi-residue analysis of 3 β-agonists, zilpaterol, clenbuterol, and ractopamine in a variety of meat samples by liquid chromatography-tandem mass spectrometry (LC-MS/MS)
  • QuEChERS-based preparation of two types of animal tissue samples, muscle and viscera, for the analysis of seven β-agonists by liquid chromatography/tandem mass spectrometry
  • Development and validation of an LC-MS/MS method to estimate zilpaterol, ractopamine, and clenbuterol in bovine tissue samples
  • Simultaneous quantitative determination of spectinomycin, halquinol, zilpaterol, and melamine in animal feed samples by LC-MS/MS

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Pictograms

Health hazardExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - STOT RE 1

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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J L Vipham et al.
Zoonoses and public health, 62(8), 599-608 (2015-03-18)
Despite effective food safety interventions within abattoirs, Salmonella enterica remains a common contaminant of raw ground beef. Research has recently implicated peripheral lymph nodes (PLNs) as a potential route by which Salmonella contaminates ground beef. This study examined the efficacy
Weilin L Shelver et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 35(8), 1519-1529 (2018-04-13)
Zilpaterol is a β-adrenergic agonist feed additive approved in the United States to increase weight gain and improve feed efficiency of cattle. A zilpaterol immunochromatographic assay was developed as an economical and user-friendly rapid detection method for zilpaterol and validated
A Rivera-Villegas et al.
Asian-Australasian journal of animal sciences, 32(2), 209-216 (2018-07-31)
We compare the effects of three different approved sources of supplemental zilpaterol on growth-performance responses and carcass characteristics of finishing lambs. Twenty four Pelibuey×Katahdin lambs (46.75±2.43 kg) were used in a 33-day feeding trial. Lambs were fed a dry rolled
Natalia Cernicchiaro et al.
Foodborne pathogens and disease, 13(9), 517-525 (2016-06-16)
The efficacy of a Salmonella vaccine for reducing fecal shedding of Salmonella during the finishing period and lymph node (LN) carriage at harvest was investigated in commercial feedlot cattle. The study was designed as a pen-level randomized complete block with
P J Kononoff et al.
Journal of animal science, 95(1), 194-200 (2017-02-09)
A total of 2,948 steers (mean initial BW = 568.9 ± 49.4 kg) were used to evaluate the effect of the LEP R25C SNP genotype on feed intake, growth performance, and carcass characteristics over time. Steers were grouped into 5

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