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762016

Sigma-Aldrich

3-Azido-1-propanamine

≥95%

Synonym(s):

3-Azidopropylamine

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About This Item

Empirical Formula (Hill Notation):
C3H8N4
CAS Number:
88192-19-2
Molecular Weight:
100.12
MDL number:
MFCD11046568
UNSPSC Code:
12352116
PubChem Substance ID:
329766597
NACRES:
NA.22

Quality Level

100

Assay

≥95%

form

liquid

reaction suitability

reaction type: click chemistry

refractive index

n20/D 1.471

density

1.020 g/mL at 25 °C

storage temp.

−20°C

SMILES string

NCCCN=[N+]=[N-]

InChI

1S/C3H8N4/c4-2-1-3-6-7-5/h1-4H2

InChI key

OYBOVXXFJYJYPC-UHFFFAOYSA-N

General description

3-Azido-1-propanamine can be used to functionalize:
  • Bismethylolpropionic acid (bis-MPA) monomers with azide functional group to generate high-generation dendrimers.,
  • Clickable zinc tetraphenylporphyrin scaffold with an azido group through click chemistry applicable in photodynamic therapy.

Application

Amine modified azide for click chemistry.
3-Azido-1-propanamine may be used in the synthesis of mannopyranoside dendrimers for studying multivalent carbohydrate-protein interactions.

Pictograms

FlameSkull and crossbones
GHS02,GHS06

Signal Word

Danger

Hazard Statements

H226,H301

Hazard Classifications

Acute Tox. 3 Oral - Flam. Liq. 3

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

140.0 °F

Flash Point(C)

60 °C

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Certificates of Analysis (COA)

Lot/Batch Number
MKCV8051
MKCT7883
MKCT4587
MKCS3343
MKCQ8517

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Xiaoqiang Chen et al.
Biomaterials, 122, 130-140 (2017-01-24)
The development of multifunctional reagents for simultaneous specific near-infrared (NIR) imaging and phototherapy of tumors is of great significance. This work describes the design of a cathepsin B-activated fluorescent probe (CyA-P-CyB) and its applications as an NIR imaging probe for
Dual display of proteins on the yeast cell surface simplifies quantification of binding interactions and enzymatic bioconjugation reactions.
Lim S, et al.
Biotechnology Journal, 12(5) (2017)
Two-dimensional ultrafast vibrational spectroscopy of azides in ionic liquids reveals solute-specific solvation
Dutta S, et al.
Physical Chemistry Chemical Physics, 17(40), 26575-26579 (2015)
Synthesis of mono-, di-and triporphyrin building blocks by click chemistry for photodynamic therapy application
Gazzali AM, et al.
Tetrahedron, 73(5), 532-541 (2017)
Synthesis and solvodynamic diameter measurements of closely related mannodendrimers for the study of multivalent carbohydrate?protein interactions.
Chabre YM, et al.
Beilstein Journal of Organic Chemistry, 10, 1524-1524 (2014)
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