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Sigma-Aldrich

Poly(2-hydroxyethyl methacrylate)

average Mv 20,000

Synonym(s):

Poly(2-HEMA), Poly-HEMA

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About This Item

Linear Formula:
(C6H10O3)n
CAS Number:
25249-16-5
MDL number:
MFCD00084374
UNSPSC Code:
12162002
PubChem Substance ID:
24877667
NACRES:
NA.23

form

powder

Quality Level

100

mol wt

average Mv 20,000

transition temp

Tg 84.8 °C

density

1.15 g/mL at 25 °C (lit.)

SMILES string

CC(=C)C(=O)OCCO

InChI

1S/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H3

InChI key

WOBHKFSMXKNTIM-UHFFFAOYSA-N

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Application

  • Hydrogen-bonds structure in poly(2-hydroxyethyl methacrylate) studied by temperature-dependent infrared spectroscopy: Investigates the hydrogen-bond structure in poly(2-hydroxyethyl methacrylate) (PHEMA) using temperature-dependent IR spectroscopy. (S Morita, 2014).
  • Transparent and tough poly(2-hydroxyethyl methacrylate) hydrogels prepared in water/IL mixtures: Describes the development of tough and transparent PHEMA hydrogels for potential use in various biomedical applications. (Y Liu et al., 2020).
  • Reduced cell attachment to poly(2-hydroxyethyl methacrylate)-coated ventricular catheters in vitro: Examines how PHEMA coatings can reduce cell attachment, which is beneficial for biomedical devices like catheters. (BW Hanak et al., 2018).
  • Surface modification of poly(2-hydroxyethyl methacrylate) hydrogel for contact lens application: Studies modifications to PHEMA hydrogels to improve their suitability for contact lens applications. (M Kazemi Ashtiani, M Zandi, 2018).

Physical form

Water-swellable polymer. Hydrogel.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCS6969
MKCQ0362
MKCH9257
MKCG3134
MKCC0598

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Damla Cetin et al.
Journal of materials science. Materials in medicine, 23(11), 2803-2812 (2012-08-09)
The effectiveness of poly(2-hydroxyethyl methacrylate)-gelatin superporous hydrogels (pHEMA-gelatin SPHs) was investigated for bone tissue engineering. The cell culture studies were performed with preosteoblastic MC3T3-E1 cells. Dynamic culture conditions were provided using 100 ml spinner flask rotating at 50 rpm. According
M Rafiqul Islam et al.
Journal of nanoscience and nanotechnology, 13(1), 603-606 (2013-05-08)
Biocompatible magnetic nanocomposites of Fe-AuNPs and poly(2-hydroxylethyl methacrylate) (PHEMA) were employed as a strategic protein immobilization platform. The hybrid magnetic nanocomposites were prepared by applying a 'grafting to' ATRP protocol. Fe-AuNPs having Fe core and Au shell were initially prepared
Kazım Köse et al.
Artificial cells, nanomedicine, and biotechnology, 41(1), 13-20 (2012-11-01)
The purpose of this article is to synthesize poly(hydroxyethyl methacrylate-N-methacryloyl-(L)-tryptophan) [mPHEMATrp] magnetic nanoparticles for lysozyme purification from chicken egg white. mPHEMATrp nanoparticles (38 nm in diameter) were synthesized by surfactant-free emulsion polymerization. Specific surface area of the mPHEMATrp nanoparticles was
Yan Fang et al.
Langmuir : the ACS journal of surfaces and colloids, 28(37), 13318-13324 (2012-08-28)
We present a detailed picture to screen general ligands from simple chemicals for fabricating affinity surface to glycosidase enzymes. The surface was constructed by grafting poly(2-hydroxyethyl methacrylate) (PHEMA) brush on SPR gold chip via surface-initiated atom-transfer radical polymerization, after which
Müge Andaç et al.
Journal of molecular recognition : JMR, 25(11), 555-563 (2012-10-31)
A new composite protein-imprinted macroporous cryogel was prepared for depletion of albumin from human serum prior to use in proteom applications. Polyhydroxyethyl-methacylate-based molecularly imprinted polymer (MIP) composite cryogel was prepared with high gel fraction yields up to 83%, and its
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