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Supelco

Discovery® HS F5 (3 µm) HPLC Columns

L × I.D. 2 cm × 2.1 mm Supelguard Guard Cartridge, pkg of 2 ea, Guard Cartridge holder required for use

Synonym(s):

Discovery Pentafluorophenyl PFP HPLC Guard-Column

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About This Item

UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52

product name

Discovery® HS F5 Supelguard Cartridge, 3 μm particle size, L × I.D. 2 cm × 2.1 mm

material

stainless steel column

Agency

suitable for USP L43

product line

Discovery®

feature

endcapped

packaging

pkg of 1 kit

technique(s)

HPLC: suitable
LC/MS: suitable

L × I.D.

2 cm × 2.1 mm

surface area

300 m2/g

matrix

fully porous particle

matrix active group

PFP (pentafluorophenyl) phase

particle size

3 μm

pore size

120 Å

operating pH

2-8

application(s)

food and beverages

compatibility

use to protect Discovery HS F5

separation technique

reversed phase

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Application

Discovery® HS F5 supelguard cartridge may be used with Discovery HS F5 column for high performance liquid chromatographic analysis of tranexamic acid and rocuronium bromide in human plasma samples after extraction using solid-phase microextraction technique.

Footnote

Kit includes one cartridge, a stand-alone holder, a piece of tubing, 2 nuts and ferrules.

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Legal Information

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

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Development of SPME method for concomitant sample preparation of rocuronium bromide and tranexamic acid in plasma.
Gorynski K, et al.
Journal of Pharmaceutical and Biomedical Analysis, 92, 183-192 (2014)
Hiroyuki Kataoka et al.
Analytical and bioanalytical chemistry, 405(1), 331-340 (2012-10-16)
We have developed a simple and sensitive method for the simultaneous determination of testosterone (TES), cortisol (CRT), and dehydroepiandrosterone (DHEA) in saliva by automated online in-tube solid-phase microextraction (SPME) coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS) using a Discovery HS
Milan Nobilis et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(32), 3845-3852 (2011-11-22)
New bioanalytical SPE-HPLC-PDA-FL method for the determination of the neuroleptic drug tiapride and its N-desethyl metabolite was developed, validated and applied to xenobiochemical and pharmacokinetic studies in humans and animals. The sample preparation process involved solid-phase extraction of diluted plasma
Federica Pellati et al.
Journal of pharmaceutical and biomedical analysis, 48(2), 254-263 (2007-12-14)
In this study a pentafluorophenylpropyl (PFPP) stationary phase was applied to the fast and reliable qualitative and quantitative analysis of ephedrine alkaloids in Ephedra plant material and derivatives. A Discovery HS F5 column (150mmx4.6mm i.d., 5microm) was used, with an
Ilia Brondz et al.
Journal of pharmaceutical and biomedical analysis, 43(3), 937-944 (2006-11-03)
The drug primaquine diphosphate is used for causative treatment of malaria. Using HPLC-MS and GC-MS, this research group was previously able to show that the main contaminant of primaquine is the positional isomer quinocide [I. Brondz, D. Mantzilas, U. Klein
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