Skip to Content
Merck
All Photos(1)

Key Documents

T8950

Sigma-Aldrich

Anti-TC10 antibody produced in rabbit

1 mg/mL, affinity isolated antibody, buffered aqueous solution

Sign Into View Organizational & Contract Pricing


About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.41
Pricing and availability is not currently available.

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

mouse, human

concentration

1 mg/mL

technique(s)

western blot: 1 μg/mL using transfected COS cells

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... RHOQ(23433)
mouse ... Rhoq(104215)

Specificity

The antibody is specific for isotype TC10α and demonstrates slight cross-reactivity with TC10β.

Immunogen

synthetic peptide corresponding to amino acid residues 136-152 from human TC10.

Target description

TC10 has been classified as a member of the Rho family of GTPases and possesses characteristics most closely related to Cdc42. This family of proteins regulates a wide variety of cellular activity including cytoskeletal rearrangements, motility, prolifera

Physical form

Solution in phosphate buffered saline containing 1.0 mg/mL BSA and 0.05 % sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Theofilos Papadopoulos et al.
The Journal of biological chemistry, 290(13), 8256-8270 (2015-02-14)
Signaling at nerve cell synapses is a key determinant of proper brain function, and synaptic defects--or synaptopathies--are at the basis of many neurological and psychiatric disorders. In key areas of the mammalian brain, such as the hippocampus or the basolateral
Esther Bridges et al.
Angiogenesis, 23(3), 493-513 (2020-06-09)
Angiogenesis, the formation of new blood vessels by endothelial cells, is a finely tuned process relying on the balance between promoting and repressing signalling pathways. Among these, Notch signalling is critical in ensuring appropriate response of endothelial cells to pro-angiogenic
Aline Penna-de-Carvalho et al.
Experimental physiology, 99(12), 1663-1678 (2014-10-19)
Telmisartan has previously been used to target obesity, showing peroxisome proliferator-activated receptor (PPAR) β/δ-related effects in white adipose tissue (WAT). We sought to evaluate whether telmisartan enhances gene and protein expression of all PPAR isoforms in WAT and brown adipose

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service