SAB2500444

Anti-GAD2(GAD67) Antibody

goat polyclonal

• Synonym(s): Anti-GAD65, Anti-Glutamate decarboxylase 2
• MDL number: MFCD03455043
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• Product Name: Anti-GAD2/GAD65 antibody produced in goat, affinity isolated antibody, buffered aqueous solution
• biological source: goat
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: human, mouse, chimpanzee, rat, canine
• technique(s): indirect ELISA: suitable; western blot: suitable
• UniProt accession no.: Q05329
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... GAD2(2572)

Description

General description

Glutamate decarboxylase 2 (GAD2) is a 65kDa protein expressed in β-cells. The gene encoding this protein is localized on human chromosome 10p12.1.

Immunogen

Peptide with sequence C-TLEDNEERMSRLSK from the internal region of the protein sequence according to NP_000809.1.

Biochem/physiol Actions

Glutamate decarboxylase 2 (GAD2) is an isoform of glutamate decarboxylase, which is involved in the synthesis of γ-aminobutyric acid (GABA). GAD2 is an auto-antigen in type I diabetes and has been shown to have a role in gastric cancer.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319
• Precautionary Statements: P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable