mmunogen was a synthetic phosphorylated peptide, which represented a portion of human minichromosomal maintenance deficient 2 surrounding Serine 53 according to the numbering given in entry NP_004517.2 (GeneID 4171).
The MCM (Mini-Chromosome Maintenance) complex is a key component of the pre-replication complex involved in replication licensing which restricts DNA replication to only once per cell cycle. The MCM complex is a heterohexamer of MCM2, MCM3, MCM4, MCM5, MCM6, and MCM7. MCM2 interacts with the core MCM complex (MCM4, 6, and 7) to regulate its helicase activity.
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