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Key Documents

P5289

Sigma-Aldrich

Anti-Progesterone antibody produced in rabbit

whole antiserum, lyophilized powder

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About This Item

MDL number:
UNSPSC Code:
51111800
NACRES:
NA.41

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

whole antiserum

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

human

technique(s)

radioimmunoassay: suitable (dextran coated charcoal 3H RIA)

UniProt accession no.

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

human ... PGR(5241)

Immunogen

progesterone-11α-BSA.

Application

Anti-Progesterone antibody produced in rabbit has been used in enzyme linked immunosorbent assay (ELISA) and competitive binding assay.

Biochem/physiol Actions

Progesterone or P4 (pregn-4-ene-3,20-dione) is a female steroid hormone that belongs to the hormones class, progestogens. It is produced by majorly by ovaries, adrenal glands and placenta of humans and other species. Progesterone derived from placenta and corpus luteum is required for the maintenance of pregnancy. Progesterone inhibits the T cell mediated immune response involved in tissue rejection. The progesterone levels in females are low before ovulation and are elevated during the luteal phase.

Reconstitution

Reconstitute with 5 mL buffer: 0.05 M Tris-HCl, pH 8.0, 0.1 M sodium chloride, 0.1% gelatin and 15 mM sodium azide. Store this stock at −20 °C. Working dilution (1:10) to be discarded if unused within 12 hours.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Socially regulated reproductive development: Analysis of GnRH-1 and kisspeptin neuronal systems in cooperatively breeding naked mole-rats (Heterocephalus glaber)
Zhou S, et al.
The Journal of Comparative Neurology, 521(13), 3003-3029 (2013)
Shuzhi Zhou et al.
The Journal of comparative neurology, 521(13), 3003-3029 (2013-03-19)
In naked mole-rat (NMR) colonies, breeding is monopolized by the queen and her consorts. Subordinates experience gonadal development if separated from the queen. To elucidate the neuroendocrine factors underlying reproductive suppression/development in NMRs, we quantified plasma gonadal steroids and GnRH-1-
Prostaglandin F2alpha induces expression of activating transcription factor 3 (ATF3) and activates MAPK signaling in the rat corpus luteum
Guo N, et al.
Acta Histochemica, 117(2), 211-218 (2015)
Steroids.
N Applezweig
Chemical week, 104, 57-72 (1969-05-17)
Progesterone and maintenance of pregnancy: is progesterone nature's immunosuppressant?
P K Siiteri et al.
Annals of the New York Academy of Sciences, 286, 384-397 (1977-03-11)

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