L4420

LY-367385 hydrochloride

≥98% (HPLC)

• Synonym(s): (S)-(+)-a-amino-4-carboxy-2-methylbenzeneacetic acid
• Empirical Formula (Hill Notation): C₁₀H₁₁NO₄ ·HCl
• CAS Number: 198419-91-9
• Molecular Weight: 245.66
• MDL number: MFCD02262124
• UNSPSC Code: 12352200
• PubChem Substance ID: 329817409
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to off-white
• solubility: H₂O: >10 mg/mL
• originator: Eli Lilly
• storage temp.: room temp
• SMILES string: Cc1cc(ccc1[C@H](N)C(O)=O)C(O)=O
• InChI: 1S/C10H11NO4/c1-5-4-6(9(12)13)2-3-7(5)8(11)10(14)15/h2-4,8H,11H2,1H3,(H,12,13)(H,14,15)/t8-/m0/s1
• InChI key: SGIKDIUCJAUSRD-QMMMGPOBSA-N

Description

Application

LY-367385 hydrochloride has been used as a non-N-methyl-D-aspartate (NMDA) glutamate receptor blocker in neuronal stimulation experiment.

Biochem/physiol Actions

LY-367385 hydrochloride has an ability to inhibit induction of long-term potentiation (LTP).

LY-367385 is a selective metabotropic glutamate 1a receptor (mGlu1a) antagonist.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable