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F4928

Sigma-Aldrich

Flavin-Containing Monooxygenase-1, Microsomes human

recombinant, expressed in baculovirus infected insect cells, buffered aqueous solution

Synonym(s):

FMO-1

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About This Item

Enzyme Commission number:
UNSPSC Code:
12352204
NACRES:
NA.54

recombinant

expressed in baculovirus infected insect cells

Quality Level

form

buffered aqueous solution

specific activity

See COA for Value

mol wt

55-60 kDa

packaging

vial of 2.5 mg

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... FMO1(2326)

Biochem/physiol Actions

The FMO′s are responsible for catalyzing the oxygenation of a variety of xenobiotic and drug compounds including environmental pollutants and carcinogens which contain a nucleophilic nitrogen, sulfur, selenium, or phosphorus-containing moiety associated with their respective oxides. These enzymes are classified as Phase I or oxidative drug metabolism enzymes.

Unit Definition

One unit will catalyze the production of 1.0 picomole of methyl p-tolylsulfoxide from methyl p-tolyl sulfide per minute at pH 9.5 at 37 deg C.

Physical form

Solution in 100 mM potassium phosphate buffer, pH 7.4.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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