C7934
2-Chloro-N6-cyclopentyl-1-deazaadenosine
Synonym(s):
DCCA
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C16H21ClN4O4
CAS Number:
Molecular Weight:
368.82
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
SMILES string
OCC1OC(C(O)C1O)n2cnc3c(NC4CCCC4)cc(Cl)nc23
InChI
1S/C16H21ClN4O4/c17-11-5-9(19-8-3-1-2-4-8)12-15(20-11)21(7-18-12)16-14(24)13(23)10(6-22)25-16/h5,7-8,10,13-14,16,22-24H,1-4,6H2,(H,19,20)
InChI key
ZQSTWOIIMKNFPE-UHFFFAOYSA-N
Biochem/physiol Actions
A selective A1 adenosine receptor agonist
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Lot/Batch Number
Don't see the Right Version?
If you require a particular version, you can look up a specific certificate by the Lot or Batch number.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
L I Gobran et al.
The American journal of physiology, 258(2 Pt 1), L45-L51 (1990-02-01)
Phosphatidylcholine secretion in type II pneumocytes has been reported to be stimulated by P1 and P2 purinoceptor agonists. P1 receptors are divided into A1 and A2 subtypes with opposite effects on the levels of adenosine 3',5'-cyclic monophosphate (cAMP). Stimulated secretion
G Cristalli et al.
Journal of medicinal chemistry, 31(6), 1179-1183 (1988-06-01)
In a search for more selective A1 adenosine receptor agonists, N6-[(R)-(-)-1-methyl-2-phenethyl]-1-deazaadenosine (1-deaza-R-PIA, 3a), N6-cyclopentyl-1-deazaadenosine (1-deazaCPA, 3b), N6-cyclohexyl-1-deazaadenosine (1-deazaCHA, 3c), and the corresponding 2-chloro derivatives 2a-c were synthesized from 5,7-dichloro-3-beta-D-ribofuranosyl-3H-imidazo[4,5-b]pyridine. On the other hand, N-ethyl-1'-deoxy-1'-(1-deaza-6-amino-9H-purin-9-yl)-beta-D-ribofuranu ronamide (1-deazaNECA, 10) was prepared from
M S Dar
Pharmacology, biochemistry, and behavior, 37(4), 747-753 (1990-12-01)
To further investigate if the modulation of ethanol-induced motor incoordination is by brain adenosine A1 and/or A2 receptor, adenosine analogs with wide variability in their affinity for A1 and A2 subtypes were administered ICV and their effect on ethanol-induced (IP)
Weiwei Li et al.
Talanta, 151, 42-50 (2016-03-08)
Pyrethroid insecticides are used extensively in agriculture, and they, as well as their environmental degradates, may remain as residues on foods such as fruits and vegetables. Since pyrethroid degradates can be identical to the urinary markers used in human biomonitoring
C Cano et al.
The Journal of pharmacology and experimental therapeutics, 261(2), 660-668 (1992-05-01)
The subtype of adenosine receptor linked to cardiac prostacyclin (PGI2) synthesis, measured as immunoreactive 6-keto-PGF1 alpha, was investigated in the rabbit heart perfused with Krebs' buffer at 20 ml/min. Adenosine (6.4-50 nmol) decreased 6-keto-PGF1 alpha synthesis, coronary perfusion pressure (PP)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service