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C7013

Sigma-Aldrich

Coenzyme A–Agarose

Synonym(s):

coa-agarose

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About This Item

MDL number:
UNSPSC Code:
41106500
NACRES:
NA.56

form

lyophilized powder

extent of labeling

2-6 μmol per mL gel

matrix

cross-linked 4% beaded agarose

matrix activation

cyanogen bromide

matrix attachment

amino

matrix spacer

1 atom

swelling

1 g swells to 5-10 mL

storage temp.

−20°C

Application

Coenzyme A-agarose is an agarose conjugate, in physical form stabilized with lactose and is used in affinity chromatography, protein chromatography and nucleotide/coenzyme resins. Coenzyme A has been used in studies assessing age-related hearing loss as well as to assess organisms that survive in environments subject to changing oxygen concentrations.

Physical form

Stabilized with lactose

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Lawrence M Szewczuk et al.
Biochemistry, 47(39), 10407-10419 (2008-09-06)
Serotonin N-acetyltransferase [arylalkylamine N-acetyltransferase (AANAT)] is a key circadian rhythm enzyme that drives the nocturnal production of melatonin in the pineal. Prior studies have suggested that its light and diurnal regulation involves phosphorylation on key AANAT Ser and Thr residues
Expression pattern of oxidative stress and antioxidant defense-related genes in the aging Fischer 344/NHsd rat cochlea.
Tanaka, C., et al.
Neurobiology of Aging (2012)
J Andrés Valderrama et al.
The Journal of biological chemistry, 287(13), 10494-10508 (2012-02-04)
We have studied for the first time the transcriptional regulatory circuit that controls the expression of the box genes encoding the aerobic hybrid pathway used to assimilate benzoate via coenzyme A (CoA) derivatives in bacteria. The promoters responsible for the
Daniel L Siehl et al.
The Journal of biological chemistry, 282(15), 11446-11455 (2007-02-03)
GAT is an N-acetyltransferase from Bacillus licheniformis that was optimized by gene shuffling for acetylation of the broad spectrum herbicide, glyphosate, forming the basis of a novel mechanism of glyphosate tolerance in transgenic plants (Castle, L. A., Siehl, D. L.
K Pahan et al.
Journal of lipid research, 36(5), 986-997 (1995-05-01)
To understand the possible role of phytanoyl-CoA ligase, present in the membrane, in the oxidation of phytanic acid in the matrix of peroxisomes (Pahan, K. and I. Singh. 1993. FEBS Lett. 333: 154-158) we examined the transport of phytanic acid/phytanoyl-CoA

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