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46069

Sigma-Aldrich

Esterase from horse liver

lyophilized, powder, brown, 0.5-1.0 U/mg

Synonym(s):

HLE

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About This Item

CAS Number:
Enzyme Commission number:
EC Number:
MDL number:
UNSPSC Code:
12352204
NACRES:
NA.54
Pricing and availability is not currently available.

form

powder

quality

lyophilized

specific activity

0.5-1.0 U/mg

mol wt

Mr ~70000

color

brown

storage temp.

−20°C

Unit Definition

1 U corresponds to the amount of enzyme which hydrolyzes 1 μmol ethyl butyrate (Cat. No. 19230) per minute at pH 8.0 and 25°C

Other Notes

Sales restrictions may apply
Slightly higher ee′s can often be obtained compared to PLE-catalysis[1][2][3]

Pictograms

Health hazard

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Resp. Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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L. Blanco et al.
Tetrahedron Letters, 29, 1915-1915 (1988)
E. Fouque et al.
Synthesis, 661-661 (1989)
J.E. Guibe et al.
Tetrahedron Letters, 30, 67-67 (1989)
XieMei Tang et al.
Critical reviews in eukaryotic gene expression, 22(3), 179-187 (2012-11-13)
Tuberculosis remains one of the most prevalent and deadly infectious diseases, largely due to the emergence of multidrug-resistant and extensive drug-resistant Mycobacterium tuberculosis, especially the coinfection with HIV. Mycobacterium Ag85 complex (Ag85A, B, and C), with a carboxylesterase consensus sequence
Zhe-Yi Hu et al.
Analytical and bioanalytical chemistry, 405(5), 1695-1704 (2012-12-15)
Dabigatran etexilate (DABE) is an oral prodrug that is rapidly converted by esterases to dabigatran (DAB), a direct inhibitor of thrombin. To elucidate the esterase-mediated metabolic pathway of DABE, a high-performance liquid chromatography/mass spectrometry based metabolite identification and semi-quantitative estimation

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