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Key Documents

PHR1193

Supelco

Verapamil Related Compound F

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

3,4-Dimethoxybenzyl alcohol, Veratryl alcohol

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About This Item

Linear Formula:
(CH3O)2C6H3CH2OH
CAS Number:
Molecular Weight:
168.19
Beilstein:
639388
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

Agency

traceable to USP 1711440

API family

verapamil

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.552 (lit.)

bp

296-297 °C/732 mmHg (lit.)

density

1.157 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

COc1ccc(CO)cc1OC

InChI

1S/C9H12O3/c1-11-8-4-3-7(6-10)5-9(8)12-2/h3-5,10H,6H2,1-2H3

InChI key

OEGPRYNGFWGMMV-UHFFFAOYSA-N

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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA9009 in the slot below. This is an example certificate only and may not be the lot that you receive.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup


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Takahisa Tsukihara et al.
Applied and environmental microbiology, 74(9), 2873-2881 (2008-03-11)
Unlike general peroxidases, Pleurotus ostreatus MnP2 was reported to have a unique property of direct oxidization of high-molecular-weight compounds, such as Poly R-478 and RNase A. To elucidate the mechanism for oxidation of polymeric substrates by MnP2, a series of
Liang Mao et al.
Environmental science & technology, 44(7), 2599-2604 (2010-03-17)
We have demonstrated in our earlier work that a few natural and synthetic estrogens can be effectively transformed through reactions mediated by lignin peroxidase (LiP). The behaviors of such reactions are variously influenced by the presence of natural organic matter
Juan Ding et al.
Journal of environmental sciences (China), 20(1), 88-93 (2008-06-25)
The extracellular enzyme secretion and biodegradation of polycyclic aromatic hydrocarbons (PAHs) were studied in agitated and shallow stationary liquid cultures of Phanerochaete chrysosporium. Veratryl alcohol and Tween80 were added to cultures as lignin peroxidase (LiP) and manganese peroxidase (MnP) inducer
Yongjun Zhang et al.
Journal of hazardous materials, 176(1-3), 1089-1092 (2009-12-01)
Carbamazepine and diclofenac were frequently detected in water bodies. In this study, crude lignin peroxidase, produced from a white rot fungus Phanerochaete chrysosporium, was studied on its in vitro degradation of both drugs. The influencing parameters were studied, including pH
Robert F H Dekker et al.
International microbiology : the official journal of the Spanish Society for Microbiology, 10(3), 177-185 (2007-12-14)
The physiological requirements needed to enhance the production of laccases by the ascomycete Botryosphaeria rhodina MAMB-05 in submerged cultivation were examined under non-induced and induced (veratryl alcohol, VA) conditions. Under non-induced conditions (-VA), the initial pH, C:N ratio, and inorganic

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