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M9647

Sigma-Aldrich

D-Mannitol

ACS reagent

Synonym(s):

Mannite

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About This Item

Empirical Formula (Hill Notation):
C6H14O6
CAS Number:
69-65-8
Molecular Weight:
182.17
Beilstein:
1721898
EC Number:
200-711-8
MDL number:
MFCD00064287
UNSPSC Code:
12352201
PubChem Substance ID:
24897346
NACRES:
NA.21

grade

ACS reagent

Quality Level

200

form

powder

optical activity

[α]25/D +23.3 to +24.3°(lit.)

impurities

Reducing sugars, passes test
≤0.0008 meq/g Titratable acid
≤0.01% Insoluble matter

ign. residue

≤0.01%

loss

≤0.05% loss on drying, 105°C

color

white

useful pH range

5.0-6.5 (25 °C, 182 g/L)

mp

167-170 °C (lit.)

solubility

water: soluble 182 g/L at 20 °C (68 °F)

cation traces

heavy metals: ≤5 ppm (by ICP-OES)

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1

InChI key

FBPFZTCFMRRESA-KVTDHHQDSA-N

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Biochem/physiol Actions

A sugar alcohol sweet tastant. Used in sweetness inhibition studies.

Other Notes

To gain a comprehensive understanding of our extensive range of Sugar alcohols for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL2318
BCCM0754
BCCM4396
WXBF4446V
WXBF2236V

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D-Mannitol-1,6-13C2 ≥99 atom % 13C, ≥97% (CP)

Sigma-Aldrich

900499

D-Mannitol-1,6-13C2

Mannitol European Pharmacopoeia (EP) Reference Standard

M0200000

Mannitol

Mannitol United States Pharmacopeia (USP) Reference Standard

USP

1375105

Mannitol

Ping Wang et al.
Autophagy, 16(1), 123-139 (2019-03-27)
Autophagy is a conserved catabolic process in eukaryotes that contributes to cell survival in response to multiple stresses and is important for organism fitness. In Arabidopsis thaliana, the core machinery of autophagy is well defined, but its transcriptional regulation is
Diana Bilton et al.
Thorax, 69(12), 1073-1079 (2014-09-24)
Bronchiectasis is characterised by excessive production of mucus and pulmonary exacerbations. Inhaled osmotic agents may enhance mucociliary clearance, but few long-term clinical trials have been conducted. To determine the impact of inhaled mannitol on exacerbation rates in patients with non-cystic
Heikki O Koskela et al.
Chest, 124(4), 1341-1349 (2003-10-14)
To compare the sensitivity and validity of mannitol, histamine, and cold air challenges to demonstrate the effect of inhaled corticosteroids (ICS) in asthma. A prospective study. Seventeen patients with recently diagnosed, steroid-naive asthma who fulfilled the diagnostic criteria of Finnish
Heikki O Koskela et al.
Chest, 125(6), 1985-1992 (2004-06-11)
To define whether coughing during mannitol challenge is a nonspecific side effect of this challenge or is associated with asthma. A prospective study. University hospital. Thirty-seven steroid-naive, asthmatic subjects and 10 healthy subjects. The participants completed a symptom questionnaire, recorded
Marieke Dubois et al.
Plant physiology, 169(1), 166-179 (2015-05-23)
Leaf growth is a tightly regulated and complex process, which responds in a dynamic manner to changing environmental conditions, but the mechanisms that reduce growth under adverse conditions are rather poorly understood. We previously identified a growth inhibitory pathway regulating
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