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C3674

Sigma-Aldrich

Citric acid trisodium salt

≥98% (GC), anhydrous

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About This Item

Linear Formula:
C6H5O7Na3
CAS Number:
68-04-2
Molecular Weight:
258.07
EC Number:
200-675-3
MDL number:
MFCD00012462
UNSPSC Code:
12161700
PubChem Substance ID:
57654009
NACRES:
NA.25

grade

anhydrous

Quality Level

200

Assay

≥98% (GC)

form

powder

solubility

water: 50 mg/mL, clear, colorless

SMILES string

[Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O

InChI

1S/C6H8O7.3Na/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;/q;3*+1/p-3

InChI key

HRXKRNGNAMMEHJ-UHFFFAOYSA-K

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General description

Citric acid trisodium salt corresponds to a molecular weight of 258 Da. It has high sodium content and sieving coefficients.

Application

Citric acid trisodium salt has been used:
  • as a component of mobile phase buffer in high performance liquid chromatography analysis of dorsal striatum homogenates(124)
  • as an electrolyte for NiW co-deposition(125)
  • as a component of saline-sodium citrate (SSC) buffer for wash steps in probe hybridization(126)

Biochem/physiol Actions

Citric acid trisodium salt as a 4% solution is used commercially as an anticoagulant during blood storage. It is used in continuous renal replacement therapy (CRRT) as an regional citrate anticoagulation (RCA) agent. Citric acid trisodium salt is used as an electrostatic stabilizer for the generation of iron (II, III) oxide hollow microspheres nanoparticle.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000281410
MKCV1171
MKCV1170
MKCN9047
MKCM4871

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Regional citrate anticoagulation for RRTs in critically ill patients with AKI
Morabito S, et al.
Clinical journal of the American Society of Nephrology : CJASN, 9(12), 2173-2188 (2014)
Citrate anticoagulation for continuous renal replacement therapy (CRRT) in patients with acute kidney injury admitted to the intensive care unit
Davenport Aand Tolwani A
NDT Plus, 2(6), 439-447 (2009)
Trisodium citrate-assisted synthesis of highly water-dispersible and superparamagnetic mesoporous Fe3O4 hollow microspheres via solvothermal process
Jiang X, et al.
Journal of alloys and compounds, 636, 34-39 (2015)
Hicham Majd et al.
Biomaterials, 54, 136-147 (2015-04-25)
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