07551
Vanillylidenacetone
≥98.5%
Synonym(s):
4-(4-Hydroxy-3-methoxyphenyl)-3-buten-2-one
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About This Item
Empirical Formula (Hill Notation):
C11H12O3
CAS Number:
Molecular Weight:
192.21
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
≥98.5%
color
yellow
mp
125-130 °C
SMILES string
COc1cc(\C=C\C(C)=O)ccc1O
InChI
1S/C11H12O3/c1-8(12)3-4-9-5-6-10(13)11(7-9)14-2/h3-7,13H,1-2H3/b4-3+
InChI key
AFWKBSMFXWNGRE-ONEGZZNKSA-N
Gene Information
human ... APP(351)
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Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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D V Rajakumar et al.
Die Pharmazie, 49(7), 516-519 (1994-07-01)
The antioxidant property of dehydrozingerone and its analogs were investigated in the ferric-ascorbate induced lipid peroxidation model in rat brain homogenate. All the non phenolic compounds were either inactive or less active, while phenolic compounds with substitution at both meta
D V Rajakumar et al.
Biochemical pharmacology, 46(11), 2067-2072 (1993-12-03)
The antioxidant properties of three related compounds, dehydrozingerone, isoeugenol and eugenol, were investigated using various models. Isoeugenol was found to be the most active in inhibiting ferrous-ion-, ferric-ion- and cumene-hydroperoxide-induced lipid peroxidation in rat brain homogenates. These compounds also showed
Yizhen Liu et al.
Journal of cardiovascular pharmacology, 52(5), 422-429 (2008-11-27)
Growth factor and oxidative stress-mediated migration and proliferation of vascular smooth muscle cells (VSMCs) play a key role in the pathogenesis of atherosclerosis. The objective of this study was to assess the ability of dehydrozingerone, a structural analog of curcumin
N Motohashi et al.
Mutation research, 377(1), 17-25 (1997-06-09)
Antimutagenic activities of dehydrozingerone, benzalacetone and its analogs substituted with the hydroxyl, methoxyl or methyl group on the benzene ring were investigated by the post-treatment for UV-induced mutagenesis in Escherichia coli WP2s (uvrA). In this assay, dehydrozingerone was a poor
M Rao et al.
Journal of biochemistry, 125(2), 383-390 (1999-02-17)
We have investigated the effect of phenolic antioxidants on cisplatin-induced cytotoxicity in vero (African Green Monkey Kidney) cells and in rat renal cortical slices in vitro, and on cisplatin-induced nephrotoxicity in rats in vivo. Incubation of cisplatin with vero cells
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