03910590

(±)-Catechin hydrate

primary reference standard

• Synonym(s): trans-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol, trans-3,3′,4′,5,7-Pentahydroxyflavane
• Empirical Formula (Hill Notation): C₁₅H₁₄O₆ · xH₂O
• CAS Number: 7295-85-4
• Molecular Weight: 290.27 (anhydrous basis)
• Beilstein: 92762
• EC Number: 205-825-1
• MDL number: MFCD00149354
• UNSPSC Code: 85151701
• PubChem Substance ID: 329747836
• NACRES: NA.24

Properties

• grade: primary reference standard
• Assay: >90.0%
• form: powder
• shelf life: limited shelf life, expiry date on the label
• manufacturer/tradename: HWI
• application(s): food and beverages
• storage temp.: −20°C
• SMILES string: [H]O[H].O[C@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3
• InChI: 1S/C15H14O6.H2O/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7;/h1-5,13,15-20H,6H2;1H2/t13-,15+;/m0./s1
• InChI key: OFUMQWOJBVNKLR-NQQJLSKUSA-N

Description

General description

Catechin hydrate, a flavononol, belongs to the class of flavonoids. It is present in abundance in Siberian larch (Larix sibirica) and in silymarin extract of milk thistle seeds. Its potent chemopreventive action by virtue of the regulation of genes through the ARE-dependent pathway has been widely investigated. It also shows potential antioxidant activity against ovarian cancer cell growth, cellular melanogenesis, human breast cancer, etc.

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Application

Catechin hydrate may be used as a reference standard for the determination of the analyte in walnut leaves by high-performance liquid chromatography (HPLC).

Biochem/physiol Actions

Polyphenolic antioxidant. Used in traditional Chinese medicine.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable