Estrogen receptor 67kD hormone binding subunit. Epitope localized between aa 120-170.
Immunogen
Bovine estrogen receptor.
Epitope: a.a. 120-170
Application
Anti-Estrogen Receptor Antibody, clone AER304 is a Mouse Monoclonal Antibody for detection of Estrogen Receptor also known as ER & has been validated in EMSA, IP, WB & IHC.
Research Category Epigenetics & Nuclear Function
Research Sub Category Transcription Factors
Western blot (human)
Immunoprecipitation (human)
Immunohistochemistry (mouse)
Optimal working dilutions must be determined by the end user.
Linkage
Replaces: 04-227
Physical form
Liquid
Storage and Stability
Maintain at -20°C in undiluted aliquots for up to one year. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Breast cancer research and treatment, 166(3), 681-693 (2017-08-16)
We previously identified small molecules that fit into a BRCA1-binding pocket within estrogen receptor-alpha (ERα), mimic the ability of BRCA1 to inhibit ERα activity ("BRCA1-mimetics"), and overcome antiestrogen resistance. One such compound, the hydrochloride salt of NSC35446 ("NSC35446.HCl"), also inhibited
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