8.16146

1-Methylpyrrolidine

for synthesis

• Synonym(s): 1-Methylpyrrolidine
• Empirical Formula (Hill Notation): C₅H₁₁N
• CAS Number: 120-94-5
• Molecular Weight: 85.15
• MDL number: MFCD00003173
• UNSPSC Code: 12352005
• EC Index Number: 204-438-5
• NACRES: NA.22

Properties

• vapor pressure: 100 hPa ( 20 °C)
• Quality Level: 200
• Assay: ≥98.0% (GC)
• form: liquid
• autoignition temp.: 170 °C (DIN 51794)
• potency: 280 mg/kg LD₅₀, oral (Rat)
• expl. lim.: 1.1-9.1 % (v/v)
• pH: 11.3 (1 g/L in H₂O)
• bp: 81 °C/1013 hPa
• mp: <-80 °C
• transition temp: flash point -3 °C
• solubility: 213 g/L
• density: 0.799 g/cm³ at 20 °C
• storage temp.: 2-30°C
• SMILES string: N1(CCCC1)C
• InChI: 1S/C5H11N/c1-6-4-2-3-5-6/h2-5H2,1H3
• InChI key: AVFZOVWCLRSYKC-UHFFFAOYSA-N

Description

General description

1-Methylpyrrolidine is a heterocyclic organic compound that serves as a base and catalyst in organic reactions, such as aldol condensations, acylations, and cyclization reactions. Additionally, it is used as a solvent for certain polymerization processes due to its ability to dissolve both polar and non-polar substances. It exhibits strong nucleophilic properties because of the lone pair of electrons on its nitrogen atom, making it highly reactive towards electrophiles. This property enables its use in alkylation, acylation, and substitution reactions, facilitating the synthesis of diverse nitrogen-containing compounds.

Analysis Note

Assay (GC, area%): ≥ 98.0 % (a/a)
Identity (IR): passes test

Safety Information

• Pictograms: GHS02,GHS05,GHS06,GHS09
• Signal Word: Danger
• Hazard Statements: H225 - H301 - H314 - H332 - H411
• Precautionary Statements: P210 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Aquatic Chronic 2 - Flam. Liq. 2 - Skin Corr. 1A
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): -0.4 °F - closed cup
• Flash Point(C): -18 °C - closed cup