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178422

Sigma-Aldrich

Anti-Apolipoprotein A-I Rabbit pAb

liquid, Calbiochem®

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

form

liquid

contains

≤0.1% sodium azide as preservative

species reactivity

human

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

isotype

IgG

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

General description

Anti-Apolipoprotein A-I, rabbit polyclonal, recognizes human apolipoprotein A-I. Does not cross-react with other apolipoproteins. It is validated for ELISA and Western blotting.
Rabbit polyclonal antibody purified by ammonium sulfate precipitation and DEAE-cellulose ion exchange chromatography. Recognizes the apolipoprotein A-I protein.
Recognizes human apolipoprotein A-I. Does not cross-react with other human apolipoproteins.
  • Antibody Target Gene Symbol: APOA1
  • Target Synonym: Ai, ALP-1, Apo1a, APOA-I, APOLIPOPROTEIN A-I, APOLIPOPROTEIN A-I G1, APOLIPOPROTEIN A1, Brp-14, HDLA1, LP(A-I), Ltw-1, Lvtw-1, MGC102525, MGC117399, Sep-1, Sep-2
  • Entrez Gene Name: apolipoprotein A-I
  • Hu Entrez ID: 335 (Related Antibodies: 178474, 178472, 178470, 178463)
  • Mu Entrez ID: 11806
  • Rat Entrez ID: 25081
  • Immunogen

    Human
    full length, human apolipoprotein A-I

    Application

    ELISA (≥1:800)

    Immunoblotting (1:1000)

    Packaging

    Please refer to vial label for lot-specific concentration.

    Warning

    Toxicity: Standard Handling (A)

    Physical form

    In PBS.

    Reconstitution

    Following initial thaw, aliquot and freeze (-20°C).

    Other Notes

    Does not cross-react with Apolipoprotein A-II, B, C-I, C-II, C-III or E by immunoblotting. Variables associated with assay conditions will dictate the proper working dilution.

    Legal Information

    CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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    Storage Class Code

    10 - Combustible liquids

    WGK

    WGK 1

    Flash Point(F)

    Not applicable

    Flash Point(C)

    Not applicable


    Certificates of Analysis (COA)

    Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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    Elias N Glaros et al.
    Journal of lipid research, 49(2), 324-331 (2007-11-06)
    The serine palmitoyl transferase inhibitor myriocin potently suppresses the development of atherosclerosis in apolipoprotein E (apoE) gene knockout (apoE(-/-)) mice fed a high-fat diet. This is associated with reduced plasma sphingomyelin (SM) and glycosphingolipid levels. Furthermore, oral administration of myriocin
    John T Melchior et al.
    Journal of lipid research, 58(7), 1374-1385 (2017-05-10)
    HDLs are a family of heterogeneous particles that vary in size, composition, and function. The structure of most HDLs is maintained by two scaffold proteins, apoA-I and apoA-II, but up to 95 other "accessory" proteins have been found associated with
    W Sean Davidson et al.
    Journal of lipid research, 57(4), 674-686 (2016-02-26)
    HDL cholesterol (HDL-C) efflux function may be a more robust biomarker of coronary artery disease risk than HDL-C. To study HDL function, apoB-containing lipoproteins are precipitated from serum. Whether apoB precipitation affects HDL subspecies composition and function has not been
    Roshni R Singaraja et al.
    Circulation, 114(12), 1301-1309 (2006-08-31)
    Extrahepatic tissues have long been considered critical contributors of cholesterol to nascent HDL particles in the reverse cholesterol transport pathway, in which ABCA1 plays the crucial role. Recent studies, however, including both overexpression and deletion of ABCA1 selectively in the
    Sven Kinzebach et al.
    BMC cell biology, 14, 48-48 (2013-10-31)
    Multilineage differentiation, immunomodulation and secretion of trophic factors render mesenchymal stromal cells (MSC) highly attractive for clinical application. Human platelet derivatives such as pooled human platelet lysate (pHPL) and thrombin-activated platelet releasate in plasma (tPRP) have been introduced as alternatives

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